Hermiz John, Rogers Nick, Kaestner Erik, Ganji Mehran, Cleary Dan, Snider Joseph, Barba David, Dayeh Shadi, Halgren Eric, Gilja Vikash
Annu Int Conf IEEE Eng Med Biol Soc. 2016 Aug;2016:4511-4514. doi: 10.1109/EMBC.2016.7591730.
Open source electrophysiology (ephys) recording systems have several advantages over commercial systems such as customization and affordability enabling more researchers to conduct ephys experiments. Notable open source ephys systems include Open-Ephys, NeuroRighter and more recently Willow, all of which have high channel count (64+), scalability, and advanced software to develop on top of. However, little work has been done to build an open source ephys system that is clinic compatible, particularly in the operating room where acute human electrocorticography (ECoG) research is performed. We developed an affordable (<; $10,000) and open system for research purposes that features power isolation for patient safety, compact and water resistant enclosures and 256 recording channels sampled up to 20ksam/sec, 16-bit. The system was validated by recording ECoG with a high density, thin film device for an acute, awake craniotomy study at UC San Diego, Thornton Hospital Operating Room.
开源电生理（ephys）记录系统相对于商业系统具有若干优势，例如可定制性和可承受性，这使得更多研究人员能够进行电生理实验。值得注意的开源电生理系统包括Open-Ephys、NeuroRighter以及最近的Willow，它们都具有高通道数（64个以上）、可扩展性以及可在其基础上进行开发的先进软件。然而，在构建与临床兼容的开源电生理系统方面所做的工作很少，特别是在进行急性人类皮层脑电图（ECoG）研究的手术室中。我们开发了一种价格实惠（<10,000美元）的开放式研究系统，该系统具有用于患者安全的电源隔离、紧凑且防水的外壳以及256个记录通道，采样率高达20ksam/秒，16位。该系统通过在加州大学圣地亚哥分校索顿医院手术室使用高密度薄膜设备进行急性清醒开颅手术研究来记录ECoG进行了验证。
