Szulińska Monika, Stępień Marta, Kręgielska-Narożna Matylda, Suliburska Joanna, Skrypnik Damian, Bąk-Sosnowska Monika, Kujawska-Łuczak Magdalena, Grzymisławska Małgorzata, Bogdański Paweł
Department of Education and Obesity Treatment and Metabolic Disorders, Poznań University of Medical Sciences , Poznań , Poland.
Department of Human Nutrition and Hygiene, Poznań University of Life Sciences , Poznań , Poland.
Food Nutr Res. 2017 Mar 3;61(1):1295525. doi: 10.1080/16546628.2017.1295525. eCollection 2017.
Recent studies indicate the important role of chronic inflammation and oxidative stress in the pathogenesis of hypertension. Green tea, due to the high content of catechins, shows high antioxidant activity. To determine the effect of supplementation with green tea extract on the blood pressure, on the concentration of selected parameters of inflammation and antioxidant status in the model of high-sodium-diet induced hypertension. The study lasted 42 days. The experimental population consisted of 30 rats. The rats were divided into three groups. The rats in the control group were fed a standard diet with 35 g of NaCl per kg of diet, in the second group hypertensive rats were fed a standard diet with NaCl (35 g/kg diet) and with an extract of green tea (2 g/kg diet). The third group consisted of hypertensive rats fed a standard diet with NaCl (35 g/kg diet), and 4 g of green tea extract/kg diet. Supplementation with green tea had no effect on body mass of rats on a high-sodium diet. At the end of the experiment systolic blood pressures in SH2 and SH4 groups were significantly lower than in the control group SK. The SH4 group was characterized by a significantly lower diastolic blood pressure value and concentration of TNF-α in comparison to the SK group. The rats from both SH2 and SH4 groups were characterized by higher total antioxidant status values compared to the control group. The mechanism of the beneficial effects of green tea on blood pressure is not clear, but it is believed that it is related to its omnidirectional properties. Supplementation of green tea has a beneficial effect on blood pressure, markers of inflammation and antioxidant status in an experimental model of hypertension.
近期研究表明，慢性炎症和氧化应激在高血压发病机制中发挥着重要作用。绿茶因含有高含量的儿茶素，具有较高的抗氧化活性。为确定补充绿茶提取物对高盐饮食诱导的高血压模型中血压、炎症相关选定参数浓度及抗氧化状态的影响。该研究持续了42天。实验群体由30只大鼠组成。大鼠被分为三组。对照组大鼠喂食每千克饮食含35克氯化钠的标准饮食，第二组高血压大鼠喂食含氯化钠（35克/千克饮食）和绿茶提取物（2克/千克饮食）的标准饮食。第三组由喂食含氯化钠（35克/千克饮食）和4克绿茶提取物/千克饮食的标准饮食的高血压大鼠组成。补充绿茶对高盐饮食大鼠的体重没有影响。实验结束时，SH2组和SH4组的收缩压显著低于对照组SK。与SK组相比，SH4组的舒张压值和TNF-α浓度显著更低。与对照组相比，SH2组和SH4组大鼠的总抗氧化状态值更高。绿茶对血压产生有益作用的机制尚不清楚，但据信这与其多方面特性有关。在高血压实验模型中，补充绿茶对血压、炎症标志物及抗氧化状态具有有益作用。
