Alassaf Fawaz A, Jasim Mahmood H M, Alfahad Mohanad, Qazzaz Mohannad E, Abed Mohammed N, Thanoon Imad A-J
Mosul University College of Pharmacy, Department of Pharmacology and Toxicology, Mosul, Iraq
Mosul University College of Pharmacy, Department of Pharmaceutical Chemistry, Mosul, Iraq
Turk J Pharm Sci. 2021 Sep 1;18(4):405-409. doi: 10.4274/tjps.galenos.2020.50024.
Bee propolis is a natural substance that is used in traditional medicine due to its versatile pharmacological actions. This study evaluates whether short term use of bee propolis supplementation could have an impact on glycemic control in healthy individuals.
A single daily dose of 1000 mg of bee propolis was administered orally to a total of 34 healthy individuals for 60 days. Body weight, body mass index (BMI), fasting blood glucose (FBG), glycosylated hemoglobin (HbA1c), and insulin resistance were measured in all participants before and after the use of bee propolis.
The results of this study showed that bee propolis was associated with a significant increase in body weight and BMI of healthy volunteers. Bee propolis supplementation decreased FBG and HbA1c, but did not affect insulin resistance.
Based on these results, bee propolis supplementation has a potential effect on glycemic control in healthy individuals and this should be considered when using this supplement in medical conditions.
蜂胶是一种天然物质，因其多样的药理作用而被用于传统医学。本研究评估短期补充蜂胶是否会对健康个体的血糖控制产生影响。
共34名健康个体口服每日单剂量1000毫克蜂胶，持续60天。在所有参与者使用蜂胶前后测量体重、体重指数（BMI）、空腹血糖（FBG）、糖化血红蛋白（HbA1c）和胰岛素抵抗。
本研究结果表明，蜂胶与健康志愿者的体重和BMI显著增加有关。补充蜂胶可降低FBG和HbA1c，但不影响胰岛素抵抗。
基于这些结果，补充蜂胶对健康个体的血糖控制有潜在作用，在医疗状况下使用这种补充剂时应予以考虑。
