Beer Christiane, Kolstad Henrik A, Søndergaard Klaus, Bendstrup Elisabeth, Heederik Dick, Olsen Karen E, Omland Øyvind, Petsonk Edward, Sigsgaard Torben, Sherson David L, Schlünssen Vivi
Department of Public Health, Section for Environment, Occupation and Health, Danish Ramazzini Centre, Aarhus University , Aarhus , Denmark.
Department of Occupational Medicine, Danish Ramazzini Centre, Aarhus University Hospital , Aarhus , Denmark.
Eur Clin Respir J. 2017 Jan 3;4(1):1264711. doi: 10.1080/20018525.2017.1264711. eCollection 2017.
: Exposure to coal dust can cause interstitial lung disease (ILD), but whether this is due to pure coal or to the contents of quartz in coal is less clear. Here, we systematically reviewed the relation between 'pure coal' and ILD. : In a systematic review based on PRISMA criteria 2945 articles were identified. Strict eligibility criteria, which evaluated the 'pure coal effect', led to the inclusion of only nine studies. : Among these nine studies six studies indicated an independent effect of the non-quartz part of coal on the development and progression of ILD, two did not demonstrate an effect and one was inconclusive. : Although an independent effect of non-quartz coal dust on the development of ILD is supported, due to methodological limitations the evidence is limited and further evidence is needed.
接触煤尘可导致间质性肺病（ILD），但这是由于纯煤还是煤中石英成分所致尚不太明确。在此，我们系统回顾了“纯煤”与ILD之间的关系。：在一项基于PRISMA标准的系统评价中，共识别出2945篇文章。严格的纳入标准对“纯煤效应”进行了评估，最终仅纳入了9项研究。：在这9项研究中，6项研究表明煤的非石英部分对ILD的发生和进展具有独立影响，2项研究未显示出这种影响，1项研究结果不明确。：尽管非石英煤尘对ILD发生具有独立影响这一观点得到了支持，但由于方法学上的局限性，证据有限，仍需进一步的证据。
