Kronborg-White Sissel, Folkersen Birgitte, Rasmussen Torben Riis, Voldby Nina, Madsen Line Bille, Rasmussen Finn, Poletti Venerino, Bendstrup Elisabeth
Department of Respiratory Diseases and Allergy, Aarhus University Hospital , Denmark.
Department of Pathology, Aarhus University Hospital , Denmark.
Eur Clin Respir J. 2017 Jan 9;4(1):1274099. doi: 10.1080/20018525.2016.1274099. eCollection 2017.
: Transbronchial cryobiopsies (cTBB) has emerged as a new method for obtaining lung tissue biopsies in the diagnosis of interstitial lung diseases (ILDs). Until now, it has been used in a few highly specialized interventional centers and has shown promising results in obtaining a definite diagnosis of ILDs. : All patients undergoing a cTBB between November 2015 and June 2016 were included in this case series study. Data on patient demographics, high-resolution computed tomography patterns, size and number of biopsies, histology patterns, the contribution to a confident diagnosis and complications were registered. : Thirty-eight patients underwent cTBB in the period. cTBB contributed to the diagnosis in 28 (74%) of the 38 patients. Only few complications were observed; pneumothorax was the most frequent complication (10 patients, 26%). In six patients, local bleeding occurred during the procedure and was easily controlled by a Fogarty catheter balloon and in some cases tranexamic acid. : Performing cTBB in the diagnostics of ILDs is a safe and feasible procedure. cTBB resulted in a confident diagnosis in 74% of cases.
经支气管冷冻活检（cTBB）已成为获取肺组织活检用于间质性肺疾病（ILDs）诊断的一种新方法。到目前为止，它已在少数高度专业化的介入中心使用，并在明确ILDs诊断方面显示出有前景的结果。：2015年11月至2016年6月期间接受cTBB的所有患者均纳入本病例系列研究。记录了患者人口统计学数据、高分辨率计算机断层扫描模式、活检的大小和数量、组织学模式、对明确诊断的贡献以及并发症情况。：在此期间，38例患者接受了cTBB。cTBB对38例患者中的28例（74%）的诊断有帮助。仅观察到少数并发症；气胸是最常见的并发症（10例患者，26%）。6例患者在操作过程中出现局部出血，通过Fogarty导管球囊并在某些情况下使用氨甲环酸很容易得到控制。：在ILDs诊断中进行cTBB是一种安全可行的操作。cTBB在74%的病例中得出了明确的诊断。
