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儿童恶性肾肿瘤

Malignant renal tumors in children.

作者信息

Lee Justin Scott, Sanchez Thomas Ray, Wootton-Gorges Sandra

机构信息

Department of Radiology; Division of Pediatric Radiology, University of California, Davis Medical Center and Children's Hospital, Sacramento, CA, USA.

出版信息

J Kidney Cancer VHL. 2015 May 10;2(3):84-89. doi: 10.15586/jkcvhl.2015.29. eCollection 2015.

DOI:10.15586/jkcvhl.2015.29
PMID:28326263
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC5345535/
Abstract

Renal malignancies are common in children. While the majority of malignant renal masses are secondary to Wilms tumor, it can be challenging to distinguish from more aggressive renal masses. For suspicious renal lesions, it is crucial to ensure prompt diagnosis in order to select the appropriate surgical procedure and treatment. This review article will discuss the common differential diagnosis that can be encountered when evaluating a suspicious renal mass in the pediatric population. This includes clear cell sarcoma of the kidney, malignant rhabdoid tumor, renal medullary carcinoma and lymphoma.

摘要

肾恶性肿瘤在儿童中很常见。虽然大多数肾恶性肿块继发于肾母细胞瘤,但要将其与更具侵袭性的肾肿块区分开来可能具有挑战性。对于可疑的肾脏病变,确保及时诊断以选择合适的手术方法和治疗至关重要。这篇综述文章将讨论在评估儿科人群中可疑肾肿块时可能遇到的常见鉴别诊断。这包括肾透明细胞肉瘤、恶性横纹肌样瘤、肾髓质癌和淋巴瘤。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6f6b/5345535/d05d942dcbef/jkcvhl-2-84-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6f6b/5345535/5560cb817670/jkcvhl-2-84-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6f6b/5345535/d05d942dcbef/jkcvhl-2-84-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6f6b/5345535/5560cb817670/jkcvhl-2-84-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6f6b/5345535/d05d942dcbef/jkcvhl-2-84-g002.jpg

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1
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Paediatric renal tumors: An insight into molecular characteristics, histomorphology and syndromic association.小儿肾肿瘤:对分子特征、组织形态学及综合征关联的深入见解
World J Nephrol. 2025 Jun 25;14(2):99380. doi: 10.5527/wjn.v14.i2.99380.
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Association of Wilms Tumor with Crossed Fused Renal Ectopia in Children: A Case Report.

本文引用的文献

1
Extra-cranial Malignant Rhabdoid Tumor in Children: A Single Institute Experience.儿童颅外恶性横纹肌样瘤:单机构经验
Cancer Res Treat. 2015 Oct;47(4):889-96. doi: 10.4143/crt.2013.176. Epub 2015 Jan 2.
2
An approach to renal masses in pediatrics.小儿肾脏肿块的处理方法。
Pediatrics. 2015 Jan;135(1):142-58. doi: 10.1542/peds.2014-1011. Epub 2014 Dec 1.
3
WARM N COLD: malignant and benign renal tumors in children.温与冷:儿童恶性和良性肾肿瘤
儿童肾母细胞瘤与交叉融合性肾异位的关联:一例报告
J Cancer Allied Spec. 2024 Jan 22;10(1):601. doi: 10.37029/jcas.v10i1.601. eCollection 2024.
4
Wilms' Tumor in Horseshoe Kidney.马蹄肾中的肾母细胞瘤
Case Rep Nephrol Dial. 2021 Jun 17;11(2):124-128. doi: 10.1159/000514774. eCollection 2021 May-Aug.
5
Flank pain and gross hematuria: an uncommon presentation of a rare disease: Answers.
Pediatr Nephrol. 2021 Jul;36(7):2049-2051. doi: 10.1007/s00467-020-04900-0. Epub 2021 Jan 13.
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Renal Medullary Carcinoma: a Report of the Current Literature.肾髓质癌:当前文献报告
Curr Urol Rep. 2019 Jan 17;20(1):4. doi: 10.1007/s11934-019-0865-9.
Emerg Radiol. 2014 Jun;21(3):261-9. doi: 10.1007/s10140-014-1202-8. Epub 2014 Feb 26.
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Long-term survivor of relapsed stage IV malignant rhabdoid tumor of the kidney.
Pediatr Int. 2013 Apr;55(2):245-8. doi: 10.1111/j.1442-200X.2012.03663.x.
5
Children's Oncology Group's 2013 blueprint for research: renal tumors.儿童肿瘤学组 2013 年研究蓝图:肾肿瘤。
Pediatr Blood Cancer. 2013 Jun;60(6):994-1000. doi: 10.1002/pbc.24419. Epub 2012 Dec 19.
6
Focal renal lesions in pediatric patients.小儿患者的局灶性肾病变
AJR Am J Roentgenol. 2012 Dec;199(6):W668-82. doi: 10.2214/AJR.11.8082.
7
Outcomes of patients with revised stage I clear cell sarcoma of kidney treated in National Wilms Tumor Studies 1-5.国家 Wilms 肿瘤研究 1-5 中治疗的修正 I 期透明细胞肉瘤患者的结局。
Int J Radiat Oncol Biol Phys. 2013 Feb 1;85(2):428-31. doi: 10.1016/j.ijrobp.2012.04.023. Epub 2012 Jun 1.
8
Best cases from the AFIP: Wilms tumor in the setting of bilateral nephroblastomatosis.武装部队病理研究所的最佳病例:双侧肾母细胞瘤病背景下的肾母细胞瘤。
Radiographics. 2010 Sep;30(5):1421-5. doi: 10.1148/rg.305095022.
9
Management of Wilms' tumor: NWTS vs SIOP.肾母细胞瘤的管理:美国国立Wilms肿瘤研究组(NWTS)与国际小儿肿瘤学会(SIOP)的对比
J Indian Assoc Pediatr Surg. 2009 Jan;14(1):6-14. doi: 10.4103/0971-9261.54811.
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Pediatric renal leukemia: spectrum of CT imaging findings.小儿肾白血病:CT影像表现谱
Pediatr Radiol. 2008 Apr;38(4):424-30. doi: 10.1007/s00247-007-0741-5. Epub 2008 Feb 1.