Greco Federico, Sabatino Lorenzo, Sabatino Francesco, Casale Manuele, Quattrocchi Carlo Cosimo, Zobel Bruno Beomonte
Unit of Diagnostic Imaging and Unit of Otolaryngology, Università Campus Bio-Medico di Roma, Rome, Italy; Eye Unit, Ashford & St Peter's Hospitals NHS Foundation Trust, UK.
J Kidney Cancer VHL. 2016 Dec 23;3(3):11-15. doi: 10.15586/jkcvhl.2016.61. eCollection 2016.
Blepharoptosis is the drooping or inferior displacement of the upper eyelid. Blepharoptosis can be either congenital or acquired. Tumour metastasis is one of the acquired causes of blepharoptosis. The lungs, locoregional lymph nodes, bone and liver are the usual sites of metastases of renal cell carcinoma (RCC); however, unusual locations of RCC have also been reported. Herein, we describe a case of a 47-year-old man with unilateral ptosis and blurred vision due to metastatic RCC. We describe the different causes of blepharopstosis, the path that led to the diagnosis, and how RCC can metastasize to unusual anatomical regions such as the orbit. Symptoms such as exophthalmos, lid edema, diplopia, ptosis, cranial nerve paralysis or blurred vision may mime a benign disease; however, they could also be the symptoms of a systemic malignancy.
上睑下垂是指上眼睑下垂或向下移位。上睑下垂可分为先天性或后天性。肿瘤转移是后天性上睑下垂的原因之一。肺、局部淋巴结、骨骼和肝脏是肾细胞癌（RCC）常见的转移部位；然而，也有报道称肾细胞癌有不寻常的转移部位。在此，我们描述一例47岁男性因转移性肾细胞癌导致单侧上睑下垂和视力模糊的病例。我们描述了上睑下垂的不同病因、诊断过程以及肾细胞癌如何转移至眼眶等不寻常的解剖区域。眼球突出、眼睑水肿、复视、上睑下垂、颅神经麻痹或视力模糊等症状可能类似良性疾病；然而，它们也可能是全身性恶性肿瘤的症状。
