• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

胰腺癌的微创外科手术方法:最新趋势

Minimally Invasive Surgical Approaches for Pancreatic Adenocarcinoma: Recent Trends.

作者信息

Lianos Georgios D, Christodoulou Dimitrios K, Katsanos Konstantinos H, Katsios Christos, Glantzounis Georgios K

机构信息

Department of Surgery, School of Medicine, University of Ioannina, University Hospital of Ioannina, 451 10, Ioannina, Greece.

Department of Gastroenterology, School of Medicine, University of Ioannina, University Hospital of Ioannina, 451 10, Ioannina, Greece.

出版信息

J Gastrointest Cancer. 2017 Jun;48(2):129-134. doi: 10.1007/s12029-017-9934-9.

DOI:10.1007/s12029-017-9934-9
PMID:28326457
Abstract

BACKGROUND

Pancreatic resection for cancer represents a real challenge for every surgeon. Recent improvements in laparoscopic experience, minimally invasive surgical techniques and instruments make now the minimally invasive approach a real "triumph." There is no doubt that minimally invasive surgery has replaced with great success conventional surgery in many fields, including surgical oncology.

METHODS AND RESULTS

However, its progress in pancreatic resection for adenocarcinoma has been dramatically slow. Recent evidence supports the notion that minimally invasive distal pancreatectomy is safe and feasible and that is becoming the procedure of choice mainly for benign or low-grade malignant lesions in the distal pancreas. On the other side, minimally invasive pancreatoduodenectomy has not yet been widely accepted and there is enormous skepticism when applied for pancreatic head adenocarcinoma. In this review, we summarize the current evidence on the potential applications of minimally invasive surgical approaches for this aggressive, heterogeneous, and enigmatic type of cancer.

CONCLUSIONS

Moreover, the potential future applications of these approaches are discussed with the hope to improve the quality of life as well as the survival rates of pancreatic cancer patients.

摘要

背景

胰腺癌的胰腺切除术对每位外科医生来说都是一项真正的挑战。腹腔镜经验、微创外科技术和器械的最新进展使微创方法如今成为一项真正的“胜利”。毫无疑问,微创手术已在包括外科肿瘤学在内的许多领域成功取代了传统手术。

方法与结果

然而,其在胰腺癌胰腺切除术中的进展极为缓慢。近期证据支持这样一种观点,即微创远端胰腺切除术是安全可行的,并且正成为主要用于远端胰腺良性或低级别恶性病变的首选术式。另一方面,微创胰十二指肠切除术尚未被广泛接受,应用于胰头腺癌时存在极大的质疑。在本综述中,我们总结了关于微创外科手术方法在这种侵袭性、异质性且神秘的癌症类型中的潜在应用的当前证据。

结论

此外,还讨论了这些方法未来的潜在应用,以期改善胰腺癌患者的生活质量以及生存率。

相似文献

1
Minimally Invasive Surgical Approaches for Pancreatic Adenocarcinoma: Recent Trends.胰腺癌的微创外科手术方法:最新趋势
J Gastrointest Cancer. 2017 Jun;48(2):129-134. doi: 10.1007/s12029-017-9934-9.
2
Minimally Invasive Approaches to Pancreatic Surgery.胰腺手术的微创方法
Surg Oncol Clin N Am. 2016 Apr;25(2):273-86. doi: 10.1016/j.soc.2015.11.001.
3
Pancreatic cancer: Open or minimally invasive surgery?胰腺癌:开放手术还是微创手术?
World J Gastroenterol. 2016 Aug 28;22(32):7301-10. doi: 10.3748/wjg.v22.i32.7301.
4
Minimally invasive pancreatic surgery.微创胰腺手术
Semin Oncol. 2015 Feb;42(1):123-33. doi: 10.1053/j.seminoncol.2014.12.011. Epub 2014 Dec 9.
5
Minimally invasive pancreatic surgery.微创胰腺手术
Minerva Chir. 2015 Dec;70(6):437-50. Epub 2015 Nov 4.
6
[Minimally invasive and robot-assisted surgery for pancreatic cystic tumors].[胰腺囊性肿瘤的微创与机器人辅助手术]
Chirurg. 2017 Nov;88(11):934-943. doi: 10.1007/s00104-017-0496-y.
7
Laparoscopic pancreatic resection.腹腔镜胰腺切除术
Minerva Chir. 2015 Oct;70(5):355-64. Epub 2015 Jul 22.
8
Learning curve of laparoscopic and robotic pancreas resections: a systematic review.腹腔镜和机器人胰腺切除术的学习曲线:系统评价。
Surgery. 2021 Jul;170(1):194-206. doi: 10.1016/j.surg.2020.11.046. Epub 2021 Feb 2.
9
Laparoscopic or open distal pancreatectomy for benign and malignant lesions of the pancreas?腹腔镜或开放远端胰腺切除术治疗胰腺良性和恶性病变?
Minerva Chir. 2018 Apr;73(2):204-209. doi: 10.23736/S0026-4733.18.07604-6. Epub 2018 Jan 23.
10
Laparoscopic resection of pancreatic adenocarcinoma: dream or reality?腹腔镜下胰腺腺癌切除术:梦想还是现实?
World J Gastroenterol. 2014 Oct 21;20(39):14255-62. doi: 10.3748/wjg.v20.i39.14255.

引用本文的文献

1
N4-acetylcytidine acetylation of neurexin 2 in the spinal dorsal horn regulates hypersensitivity in a rat model of cancer-induced bone pain.脊髓背角中神经细胞黏附分子2的N4-乙酰胞苷乙酰化调节癌症诱导的骨痛大鼠模型中的超敏反应。
Mol Ther Nucleic Acids. 2024 Apr 23;35(2):102200. doi: 10.1016/j.omtn.2024.102200. eCollection 2024 Jun 11.
2
Impact of CRISPR/Cas9-Mediated CD73 Knockout in Pancreatic Cancer.CRISPR/Cas9介导的CD73基因敲除对胰腺癌的影响。
Cancers (Basel). 2023 Oct 3;15(19):4842. doi: 10.3390/cancers15194842.
3
Genome-Wide CRISPR Screening Identifies DCK and CCNL1 as Genes That Contribute to Gemcitabine Resistance in Pancreatic Cancer.

本文引用的文献

1
Assessment of quality outcomes for robotic pancreaticoduodenectomy: identification of the learning curve.机器人胰十二指肠切除术质量结果评估:学习曲线的确定。
JAMA Surg. 2015 May;150(5):416-22. doi: 10.1001/jamasurg.2015.17.
2
Minimally invasive pancreatic surgery.微创胰腺手术
Semin Oncol. 2015 Feb;42(1):123-33. doi: 10.1053/j.seminoncol.2014.12.011. Epub 2014 Dec 9.
3
Laparoscopic gastrectomy for gastric cancer: current evidences.腹腔镜胃癌手术:当前证据。
全基因组CRISPR筛选确定DCK和CCNL1为导致胰腺癌吉西他滨耐药的基因。
Cancers (Basel). 2022 Jun 27;14(13):3152. doi: 10.3390/cancers14133152.
4
Minimally-invasive versus open pancreatoduodenectomies with vascular resection: A 1:1 propensity-matched comparison study.微创与开放性胰十二指肠切除术联合血管切除:一项1:1倾向评分匹配比较研究。
J Minim Access Surg. 2022 Jul-Sep;18(3):420-425. doi: 10.4103/jmas.jmas_201_21.
5
Fluorescent Anti-CEA Nanobody for Rapid Tumor-Targeting and Imaging in Mouse Models of Pancreatic Cancer.荧光抗 CEA 纳米抗体用于胰腺癌小鼠模型的快速肿瘤靶向和成像。
Biomolecules. 2022 May 16;12(5):711. doi: 10.3390/biom12050711.
6
Robotic versus open pancreatic surgery: a propensity score-matched cost-effectiveness analysis.机器人与开放胰腺手术:倾向评分匹配的成本效益分析。
Langenbecks Arch Surg. 2022 Aug;407(5):1923-1933. doi: 10.1007/s00423-022-02471-2. Epub 2022 Mar 21.
7
The Effect of GPRC5a on the Proliferation, Migration Ability, Chemotherapy Resistance, and Phosphorylation of GSK-3β in Pancreatic Cancer.GPRC5a 对胰腺癌增殖、迁移能力、化疗耐药性和 GSK-3β 磷酸化的影响。
Int J Mol Sci. 2018 Jun 26;19(7):1870. doi: 10.3390/ijms19071870.
8
Identification of Prognostic Biomarkers by Combined mRNA and miRNA Expression Microarray Analysis in Pancreatic Cancer.通过联合mRNA和miRNA表达微阵列分析鉴定胰腺癌的预后生物标志物
Transl Oncol. 2018 Jun;11(3):700-714. doi: 10.1016/j.tranon.2018.03.003. Epub 2018 Apr 6.
Int J Surg. 2014 Dec;12(12):1369-73. doi: 10.1016/j.ijsu.2014.10.014. Epub 2014 Oct 31.
4
A multicenter survey on distal pancreatectomy in Italy: results of minimally invasive technique and variability of perioperative pathways.意大利远端胰腺切除术的多中心调查:微创技术结果及围手术期路径的变异性
Updates Surg. 2014 Dec;66(4):253-63. doi: 10.1007/s13304-014-0273-0. Epub 2014 Nov 28.
5
Minimally invasive pancreatectomy for cancer: a critical review of the current literature.用于癌症治疗的微创胰腺切除术:对当前文献的批判性综述
J Gastrointest Surg. 2015 Feb;19(2):375-86. doi: 10.1007/s11605-014-2695-x. Epub 2014 Nov 12.
6
Robotic surgery of the pancreas.胰腺机器人手术
World J Gastroenterol. 2014 Oct 28;20(40):14726-32. doi: 10.3748/wjg.v20.i40.14726.
7
Laparoscopic resection of pancreatic adenocarcinoma: dream or reality?腹腔镜下胰腺腺癌切除术:梦想还是现实?
World J Gastroenterol. 2014 Oct 21;20(39):14255-62. doi: 10.3748/wjg.v20.i39.14255.
8
Laparoscopic pancreatectomy: indications and outcomes.腹腔镜胰腺切除术:适应证与结果
World J Gastroenterol. 2014 Oct 21;20(39):14246-54. doi: 10.3748/wjg.v20.i39.14246.
9
The state of the art of robotic pancreatectomy.机器人胰腺切除术的技术现状。
Biomed Res Int. 2014;2014:920492. doi: 10.1155/2014/920492. Epub 2014 May 28.
10
Defining the learning curve for team-based laparoscopic pancreaticoduodenectomy.确定基于团队的腹腔镜胰十二指肠切除术的学习曲线。
Ann Surg Oncol. 2014 Nov;21(12):4014-9. doi: 10.1245/s10434-014-3839-7. Epub 2014 Jun 13.