玄参中新的环烯醚萜苷和新的肉桂酰苷。

A new iridoid glycoside and a new cinnamoyl glycoside from Scrophularia ningpoensis Hemsl.

作者信息

Zhang Jun, Ip Fanny C F, Liang Yan, Ip Nancy Y, Zhong Ba-Lian, Lai Chun-Wang, Xu Shi-Hai

机构信息

a National Engineering Research Center of Navel Orange , Gannan Normal University , Ganzhou , P.R. China.

b Division of Life Science , The Hong Kong University of Science and Technology , Hong Kong , P.R. China.

出版信息

Nat Prod Res. 2017 Oct;31(20):2361-2368. doi: 10.1080/14786419.2017.1306704. Epub 2017 Mar 22.

DOI:10.1080/14786419.2017.1306704

PMID:28326841

Abstract

A new iridoid glycoside, namely 8-O-(threo-2, 3-dihydroxyl-3-phenyl-propionoyl)-harpagide (1), along with a new cinnamoyl glycoside named as cis-sibirioside A (2), were isolated from Scrophularia ningpoensis Hemsl. Their chemical structures were completely established by spectroscopic methods and comparison with related literatures. Compound 1 exhibited moderate antifouling effect against the settlement of Balanus amphitrite larvae with IC being 13.5 μg/mL and LC > 25 μg/mL.

摘要

从玄参中分离得到一个新的环烯醚萜苷，即8-O-(苏式-2,3-二羟基-3-苯基丙酰基)-哈帕苷(1)，以及一个新的肉桂酰苷，命名为顺式西伯利亚苷A(2)。通过光谱方法并与相关文献比较，完全确定了它们的化学结构。化合物1对纹藤壶幼虫的附着表现出中等程度的防污效果，其IC为13.5μg/mL，LC>25μg/mL。