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儿童热性惊厥的复发风险

Recurrence Risk of Febrile Seizures in Children.

作者信息

Agrawal J, Poudel P, Shah G S, Yadav S, Chaudhary S, Kafle S

机构信息

Department of Pediatrics, B.P. Koirala Institute of Health Sciences, Dharan, Nepal.

出版信息

J Nepal Health Res Counc. 2016 Sep;14(34):192-196.

Abstract

BACKGROUND

Identifying children with febrile seizure who are at risk for recurrence is important so that special attention can be given to them. The objective of this study was to identify the risk factors for recurrence of febrile seizures in children.

METHODS

This prospective hospital based study was conducted from July 2013 to August 2014 'among children of 6 months to 6 years of age at Bishweshwar Prasad Koirala Institute of Health Sciences (BPKIHS), Nepal. Children meeting the selection criteria were enrolled in study. Clinical, investigation, treatment and outcome parameters were analyzed.

RESULTS

A total of 92 children with febrile seizure were enrolled in study. Males accounted for 70% and females 30%. Simple febrile seizure was present in 48% and complex febrile seizures were seen in 52%. Recurrence of seizure was seen in one third of cases. Loss of consciousness was most common post-ictal phenomenon followed by confusion and lethargy. Upper respiratory infection was the most common precipitating factor. Generalized Tonic Clonic Seizure was the most common seizure type present in 79% of cases. Significant risk factors for recurrence occurred in males (p=0.088), age less than 1 year (p=0.003). Most of the recurrence occurred within one year of first seizure.

CONCLUSIONS

Febrile Seizure is common in males. Almost one third of children with febrile seizure are at risk for recurrence. The significant risk factors for recurrences are male gender and age <1year.

摘要

背景

识别热性惊厥复发风险的儿童很重要,这样就能给予他们特别关注。本研究的目的是确定儿童热性惊厥复发的风险因素。

方法

这项前瞻性的基于医院的研究于2013年7月至2014年8月在尼泊尔比什韦什瓦尔·普拉萨德·柯伊拉腊健康科学研究所(BPKIHS)对6个月至6岁的儿童进行。符合入选标准的儿童被纳入研究。对临床、检查、治疗和结局参数进行分析。

结果

共有92例热性惊厥儿童被纳入研究。男性占70%,女性占30%。单纯性热性惊厥占48%,复杂性热性惊厥占52%。三分之一的病例出现惊厥复发。意识丧失是最常见的发作后现象,其次是意识模糊和嗜睡。上呼吸道感染是最常见的诱发因素。全身性强直阵挛性惊厥是最常见的惊厥类型,占79%的病例。复发的显著风险因素为男性(p = 0.088)、年龄小于1岁(p = 0.003)。大多数复发发生在首次发作后的一年内。

结论

热性惊厥在男性中常见。几乎三分之一的热性惊厥儿童有复发风险。复发的显著风险因素是男性性别和年龄<1岁。

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