Shrestha D, Dhakal A K, Shakya H, Shakya A, Shah S C, Mehata S
Department of Pediatrics, KIST Medical College, Lalitpur, Nepal.
Nepal Health Sector Support Programme (NHSSP), MoHP, Nepal.
J Nepal Health Res Counc. 2014 Sep-Oct;12(28):162-6.
Febrile seizure is common in children below five years of age. This study was conducted to evaluate the clinical profile of children presenting with febrile seizure in a teaching hospital.
This was a descriptive retrospective study among children presenting with febrile seizure in a teaching hospital from July 2009 to June 2013. Children between six months to six years were included in the study while patients with prior episodes of afebrile seizures, abnormal neurodevelopment and not meeting the age criteria were excluded. Patient's demographic and clinical data were collected from the in-patients records and analyzed.
This study included 103 children with febrile seizure. Out of which 67% were male. Simple febrile seizure and complex febrile seizure were observed in 76.7% and 23.3% of patients respectively. Majority of children (71.8%)had generalized tonic clonic seizure followed by tonic seizures. Most of children (72.8%) who developed first episode of seizure were below 24 months of age with the mean age of 20.7 (±12.1) months. Overall 33% of patients developed recurrence of febrile seizure and first episode of febrile seizure at age one year or below was associated with the seizure recurrence. Upper respiratory tract infections were the commonest cause of fever in these children.
Febrile seizure was observed predominantly in children below age of two years and simple febrile seizure was the ommonest variety. Recurrence of febrile seizure was common and significantly associated with the first episode of febrile seizure at the age of one year or below.
热性惊厥在五岁以下儿童中很常见。本研究旨在评估一家教学医院中热性惊厥患儿的临床特征。
这是一项描述性回顾性研究,研究对象为2009年7月至2013年6月在一家教学医院出现热性惊厥的儿童。纳入研究的儿童年龄在6个月至6岁之间,排除有既往无热惊厥发作史、神经发育异常及不符合年龄标准的患者。从住院病历中收集患者的人口统计学和临床数据并进行分析。
本研究纳入了103例热性惊厥患儿。其中67%为男性。分别有76.7%和23.3%的患者出现单纯性热性惊厥和复杂性热性惊厥。大多数儿童(71.8%)出现全身性强直阵挛发作,其次是强直发作。大多数首次发作惊厥的儿童(72.8%)年龄在24个月以下,平均年龄为20.7(±12.1)个月。总体而言,33%的患者出现热性惊厥复发,一岁及以下首次出现热性惊厥与惊厥复发相关。上呼吸道感染是这些儿童发热最常见的原因。
热性惊厥主要发生在两岁以下儿童中,单纯性热性惊厥最为常见。热性惊厥复发很常见,且与一岁及以下首次热性惊厥显著相关。