Chiappetta Sonja, Stier Christine
Department of Obesity and Metabolic Surgery, Sana Klinikum Offenbach, Offenbach am Main, Germany.
Medicine (Baltimore). 2017 Mar;96(12):e6348. doi: 10.1097/MD.0000000000006348.
Postprandial hyperinsulinemic hypoglycemia, known as late dumping syndrome, is a rare but often misdiagnosed complication after gastric surgery. The pathophysiological mechanisms are poorly understood and the treatment of this syndrome is challenging.
New-onset postsurgical late dumping syndrome after Toupet fundoplication.
Sigstad Score, OGTT, CGM.
Daily subcutaneous injection of liraglutide (0.6 mg and 1.2 mg).
Reduction in fasting and postprandial peak insulin level with improvement in symptomatic hypoglycemic events.
Liraglutide may be a novel treatment option for postprandial hyperinsulinemic hypoglycemia after gastric surgery.
餐后高胰岛素血症性低血糖,即所谓的晚期倾倒综合征,是胃手术后一种罕见但常被误诊的并发症。其病理生理机制尚不清楚,该综合征的治疗具有挑战性。
在进行图佩特胃底折叠术后出现新发的术后晚期倾倒综合征。
西格斯塔德评分、口服葡萄糖耐量试验、连续血糖监测。
每日皮下注射利拉鲁肽(0.6毫克和1.2毫克)。
空腹和餐后胰岛素峰值水平降低,有症状的低血糖事件得到改善。
利拉鲁肽可能是胃手术后餐后高胰岛素血症性低血糖的一种新的治疗选择。