Katada Yusaku, Negishi Kazuno, Watanabe Kazuhiro, Shigeno Yuta, Saiki Megumi, Torii Hidemasa, Kaido Minako, Tsubota Kazuo
Department of Ophthalmology, Keio University School of Medicine, Shinanomachi, Shinjuku-ku, Japan.
PLoS One. 2016 Mar 9;11(3):e0151094. doi: 10.1371/journal.pone.0151094. eCollection 2016.
To evaluate visual function in patients with early presbyopia using the functional visual acuity (FVA) test.
This study included 27 eyes of 27 healthy older volunteers (mean age, 44.1 ± 2.6 years) and 14 eyes of 14 healthy young volunteers (mean age, 28.4±4.8 years). The distance-corrected visual acuity (DCVA), distance-corrected near VA (DCNVA), subjective amplitude of accommodation (AA), and distance and near pupillary diameters were measured. The distance FVA and distance-corrected near FVA (DCNFVA) were measured using the FVA Measurement System. The standard Schirmer test and standard tear break-up time measurement also were performed.
The logarithm of the minimum angle of resolution (logMAR) DCVA was better than 0 in all subjects. The percentages of subjects with logMAR DCNVA below 0 was significantly lower in the presbyopia group than in the young group. The DCNFVA in the presbyopia group was significantly (P < 0.001) poorer than the DCNVA in that group. Significant linear negative correlations were seen between the DCNVA and AA (r = -0.507, P < 0.001) and the DCNFVA and AA (r = -0.681, P < 0.001) in the older subjects. Stepwise regression analysis showed that only the AA was a significant factor predictive of the DCNFVA in the presbyopia group. Tear function parameters were not adopted in the regression model.
Measurement of the DCNFVA can detect decreased AA in early presbyopia better than measurement of the conventional near VA. The DCNFVA is a good index for early presbyopia.
使用功能性视力（FVA）测试评估早期老花眼患者的视觉功能。
本研究纳入了27名健康老年志愿者的27只眼（平均年龄44.1±2.6岁）和14名健康年轻志愿者的14只眼（平均年龄28.4±4.8岁）。测量了远距矫正视力（DCVA）、远距矫正近视力（DCNVA）、主观调节幅度（AA）以及远距和近距瞳孔直径。使用FVA测量系统测量远距FVA和远距矫正近FVA（DCNFVA）。还进行了标准的Schirmer试验和标准泪膜破裂时间测量。
所有受试者的最小分辨角对数（logMAR）DCVA均优于0。老花眼组中logMAR DCNVA低于0的受试者百分比显著低于年轻组。老花眼组的DCNFVA显著（P<0.001）差于该组的DCNVA。在老年受试者中，DCNVA与AA之间（r=-0.507，P<0.001）以及DCNFVA与AA之间（r=-0.681，P<0.001）存在显著的线性负相关。逐步回归分析表明只有AA是老花眼组中DCNFVA的显著预测因素。泪液功能参数未纳入回归模型。
与传统近视力测量相比，测量DCNFVA能更好地检测早期老花眼中AA的下降。DCNFVA是早期老花眼的良好指标。
