Megna Matteo, Cantelli Mariateresa, Martellotta Donata, Calabrò Gabriella, Balato Anna, Ayala Fabio
Department of Dermatology, University of Naples Federico II.
Dermatol Online J. 2016 Sep 15;22(9):13030/qt29g4r1k4.
Aquagenic wrinkling of the palms (AWP) is an unusual and rare dermatological condition characterized by excessive palmar wrinkling, occurring within a few minutes of water exposure. Cystic fibrosis (CF) or CF carrier state associated forms, drug induced cases, and idiopathic forms have been described. We report the case of a 27-year-old woman with a 7-year history of transient excessive wrinkling of her palms after brief exposure to water. We present also a comprehensive review of the literature. We believe that AWP has been underdiagnosed thus far and we would like to encourage investigations such as sweat chloride test or genetic studies in these patients because of the association with CF or CF carrier state, particularly when AWP appears in younger ages.
掌部水致性皱纹（AWP）是一种罕见的皮肤病，其特征为手掌过度起皱，在接触水几分钟内就会出现。已描述了与囊性纤维化（CF）或CF携带者状态相关的类型、药物诱发病例和特发性类型。我们报告了一名27岁女性的病例，她有7年短暂接触水后手掌短暂过度起皱的病史。我们还对文献进行了全面综述。我们认为，到目前为止AWP一直未得到充分诊断，鉴于其与CF或CF携带者状态有关，特别是当AWP出现在较年轻时，我们鼓励对这些患者进行诸如汗液氯化物检测或基因研究等检查。
