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数字再植与翻修截肢术后长期健康相关生活质量结局

Long-Term Health-Related Quality of Life Outcomes in Digital Replantation versus Revision Amputation.

作者信息

Tessler Oren, Bartow Matthew J, Tremblay-Champagne Marie P, Lin Alex M, Landes Geneviève, Sebbag Sarah, Nikolis Andreas

机构信息

Louisiana Health Science Center, New Orleans, Louisiana.

Hôpital Pierre-Le Gardeur, Terrebonne, Quebec, Canada.

出版信息

J Reconstr Microsurg. 2017 Jul;33(6):446-451. doi: 10.1055/s-0037-1601052. Epub 2017 Mar 22.

Abstract

Earlier, digit viability judged the success of digital replantation. Now, utility health-related quality of life (HRQOL) measures can better assess the impact of digital replantation.  Overall, 264 digital injury patients were sent a regimen of utility measures: Disabilities of the Arm, Shoulder and Hand (DASH) score, European Quality of Life 5 Dimensions, visual analog scale (VAS), time trade-off (TTO), and standard gamble (SG). Overall, 51 patients responded completely to all of these-36 replantation patients and 15 revision amputation patients. The utility results of these patients were stratified between replantation versus revision amputation; dominant hand replantation versus nondominant hand replantation; and dominant hand revision amputation versus nondominant hand revision amputation.  The mean VAS score of replant (0.84) and revision amputation (0.75) groups was significantly different ( = 0.05). The mean DASH score of dominant hand replantations (29.72) and nondominant hand replantations (17.97) was significantly different ( = 0.027). The dominant hand revision amputation had higher anxiety levels in comparison to nondominant hand revision amputation ( = 0.027). Patients with two or more digits replanted showed a significant decrease in VAS, TTO, and SG scores in comparison to patients who only had one digit replanted ( = 0.009, 0.001, and 0.001, respectively).  This study suggests that HRQOL can offer better indices for outcomes of digital replantation. This shows some specific replantation cohorts have a significantly better quality of life when compared with their specific correlating revision amputation cohort. These findings can be employed to further refine indications and contraindications to replantation and help predict the quality of life outcomes.

摘要

早期,手指存活情况用于判断断指再植的成功与否。如今,与健康相关的效用生活质量(HRQOL)指标能更好地评估断指再植的影响。总体而言,向264名手指受伤患者发送了一套效用指标方案:上肢、肩部和手部功能障碍(DASH)评分、欧洲生活质量5维度量表、视觉模拟量表(VAS)、时间权衡法(TTO)和标准博弈法(SG)。总体而言,51名患者对所有这些指标都做出了完整回应——36名再植患者和15名翻修截肢患者。这些患者的效用结果按以下情况进行分层:再植与翻修截肢;优势手再植与非优势手再植;优势手翻修截肢与非优势手翻修截肢。再植组(0.84)和翻修截肢组(0.75)的平均VAS评分存在显著差异(P = 0.05)。优势手再植(29.72)和非优势手再植(17.97)的平均DASH评分存在显著差异(P = 0.027)。与非优势手翻修截肢相比,优势手翻修截肢患者的焦虑水平更高(P = 0.027)。与仅再植一根手指的患者相比,再植两根或更多手指的患者的VAS、TTO和SG评分显著降低(分别为P = 0.009、0.001和0.001)。本研究表明,HRQOL可为断指再植的结果提供更好的指标。这表明,与特定的相关翻修截肢队列相比,一些特定的再植队列的生活质量明显更好。这些发现可用于进一步完善再植的适应证和禁忌证,并有助于预测生活质量结果。

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