Lewis C J, Al-Mousawi A, Jha A, Allison K P
Department of Plastic Surgery, James Cook University Hospital, Middlesbrough, UK.
Department of Plastic Surgery, James Cook University Hospital, Middlesbrough, UK.
J Plast Reconstr Aesthet Surg. 2017 May;70(5):563-567. doi: 10.1016/j.bjps.2017.02.013. Epub 2017 Feb 27.
A multitude of household and occupational compounds have the potential to induce chemical burns to the eye and skin. Without prompt intervention, irreversible visual loss and disfigurement may prevail. Diphoterine and Hexafluorine are amphoteric and hypertonic chelating solutions used in the management of general chemical and hydrofluoric acid burns, respectively. They rapidly neutralise both acid and alkali agents without heat release and limit diffusion, making them superior to water irrigation alone. However, although Diphoterine and Hexafluorine uptake is slowly increasing in industrial workplaces, there is a paucity of education and use in both emergency departments and plastic surgery units worldwide. Herein, we present a case report of combined ocular and cutaneous acid burn treated with Diphoterine, together with a review of the current supporting literature.
众多家用和职业用化合物都有可能导致眼部和皮肤化学灼伤。若不及时干预，可能会导致不可逆转的视力丧失和毁容。Diphoterine和Hexafluorine分别是用于处理一般化学灼伤和氢氟酸灼伤的两性和高渗螯合溶液。它们能迅速中和酸和碱剂，不释放热量并限制扩散，使其优于单纯的水冲洗。然而，尽管Diphoterine和Hexafluorine在工业工作场所的使用量正在缓慢增加，但在全球范围内的急诊科和整形外科单位，对其的培训和使用却很少。在此，我们报告一例用Diphoterine治疗的眼和皮肤联合酸灼伤病例，并对当前的相关文献进行综述。
