Kishikawa Reiko, Kotoh Eiko, Oshikawa Chie, Soh Nobuo, Shimoda Terufumi, Saito Akemi, Sahashi Norio, Enomoto Tadao, Usami Atsushi, Teranishi Hidetoyo, Fujisaki Yohko, Yokoyama Toshitaka, Murayama Kohji, Imai Tohru, Fukutomi Yuma, Taniguchi Masami, Iwanaga Tomoaki
The National Hospital Organization Fukuoka Hospital Clinical Research Department.
Arerugi. 2017;66(2):97-111. doi: 10.15036/arerugi.66.97.
In Japan patients with Japanese Cedar (JC) pollinosis have increased nation widely since the latter of 1970's. The Ministry of Health and Welfare of Japanese Governments has begun to take preventive measures against JC pollinosis and airborne pollen monitoring has begun to investigate as a causative agent since 1986. We have estimated the longitudinal investigation result for successful prevention and treatment against pollinosis in Japan.
We have monitored airborne pollen all year around since July 1986 by gravitational pollen sampler, Durham's sampler, at more than 20 locations in the Japanese Islands. Pollen samples were sent to our hospital and counted pollen number per cm after stained by Calberla solution and then classified main pollen grains as a causative agent of pollinosis.
JC pollen number was the most of all, more than 40%, next cypress family, about 20%. They were occupied of more than 60% of all and they increased with the remarkable annual fluctuation as the allergen of JC pollinosis. Beech family pollen counting were also increasing and occupied about 10% of all pollen counts. In Hokkaido the prevalence of birch family pollen count was larger than that in other districts. There is cross-reactivity between beech and birch family which related with oral allergic syndrome.Perspective and Conclusion: In future new occurrences of oral allergy syndrome due to increasing allergic tree pollen grains would be appeared. The contentious pollen research should be important for patients with pollinosis in Japan.
自20世纪70年代后期以来，日本全国范围内日本柳杉花粉症患者数量不断增加。日本厚生省已开始采取预防日本柳杉花粉症的措施，自1986年起开始进行空气中花粉监测，以调查其作为致病因素的情况。我们评估了日本针对花粉症成功预防和治疗的纵向调查结果。
自1986年7月起，我们使用重力花粉采样器（Durham采样器）在日本列岛20多个地点全年监测空气中的花粉。花粉样本被送至我院，用卡尔贝拉溶液染色后计算每平方厘米的花粉数量，然后将主要花粉粒分类为花粉症的致病因素。
日本柳杉花粉数量最多，超过40%，其次是柏科，约20%。它们占所有花粉的60%以上，并且作为日本柳杉花粉症的过敏原，其数量随年度波动显著增加。山毛榉科花粉计数也在增加，约占所有花粉计数的10%。在北海道，桦木科花粉计数的患病率高于其他地区。山毛榉和桦木科之间存在与口腔过敏综合征相关的交叉反应性。展望与结论：未来，由于过敏性树木花粉粒增加，可能会出现新的口腔过敏综合征病例。有争议的花粉研究对日本的花粉症患者应该很重要。
