Bovine adenovirus type-3 infection in feedlot calves.

The frequency of bovine adenovirus type-3 (BA3) infection in 84 of 165 light feeder calves and the possible role of BA3 in inducing febrile disease and affecting weight gain performance were studied for 56 days after the calves entered a feedlot. Samples of blood for serotesting were obtained periodically, and samples for virus isolation were collected on days 28 and 56. At the time the calves entered the feedlot, 17.8% (15 of 84) had serum virus-neutralizing antibodies to BA3. During 56 days, 54.8% (46 of 84) seroconverted to BA3. Of these seroconversions, 87% took place during the first 28 days. Bovine adenovirus type-3 was isolated from 2 calves (1 isolate each on days 28 and 56). Pyrexia (greater than or equal to 39.2 C) was observed more often in BA3-infected calves than in noninfected calves. However, there was no significant (P less than 0.05) difference in weight gain between the BA3-infected and noninfected calves.