Sizov I
Vet Med Nauki. 1980;17(4):30-7.
Experiments were carried out on calves from 3 cattle-breeding farms, failing to fight respiratory disorders, aged 10-120 days, in order to prove the participation of cattle adenoviruses in the etiology of the illness. Age susceptibility, as well as the dynamics of passive and active antibodies in young calves against adenoviruses were studied with regard to technology of their breeding. It was proved that the persistence of antiadenoviral antibodies of colostral origin was determined within the limits of 4-8 weeks, whereas the infection of the young and growing calves with adenoviruses took place most frequently within the limits of 2-16 weeks after their birth and this process is greatly influenced by the regime of breeding. An earlier grouping of calves (8-10 days after their birth) advances age susceptibility, and conversely. The regrouping of calves from unsuccessful farms at the age of 20 days led to a later manifestation of adenoviral disease in the group. In the blood serum of calves from one farm were proved virus neutralizing antibodies, corresponding simultaneously to cattle adenoviruses serotypes 3 and 8, as well as precipitating ones against group specific antigens from I and II adenoviral subgroups. It was proved that 40-50% of the growing calves suffer from adenoviral infection.
为了证实牛腺病毒在该病病因中的作用,对来自3个养牛场、年龄在10 - 120天、未能抵抗呼吸道疾病的犊牛进行了实验。针对犊牛的饲养技术,研究了其年龄易感性以及幼龄犊牛体内抗腺病毒的被动和主动抗体动态。结果证明,初乳来源的抗腺病毒抗体在4 - 8周内持续存在,而幼龄和生长中的犊牛感染腺病毒最常发生在出生后2 - 16周内,且这一过程受饲养方式的极大影响。犊牛较早分组(出生后8 - 10天)会提高年龄易感性,反之亦然。20日龄时将来自饲养不佳农场的犊牛重新分组,会导致该组腺病毒疾病出现较晚。在一个农场犊牛的血清中,证实存在同时对应于牛腺病毒3型和8型血清型的病毒中和抗体,以及针对I和II腺病毒亚组的组特异性抗原的沉淀抗体。结果证明,40 - 50%的生长中的犊牛患有腺病毒感染。