Nakano Tomoyuki, Endo Shunsuke, Tetsuka Kenji, Fukushima Noriyoshi
1 Departments of General Thoracic Surgery, 2 Departments of Pathology, Jichi Medical University, 3311-1 Yakushiji, Shimotsuke, Tochigi 329-0498, Japan.
J Thorac Dis. 2016 Jan;8(1):E157-60. doi: 10.3978/j.issn.2072-1439.2016.01.16.
We herein report an asymptomatic 65-year-old male with localized pleural amyloidosis mimicking malignant pleural mesothelioma. He had a history of exposure to asbestos and was admitted for investigation of an abnormal pleural thickness detected by chest radiography. Positron emission tomography showed elevation of standardized uptake value corresponding to the pleural thickness. Partial pleurectomy including the tumor was performed for the purpose of diagnosis and local disease control. The pathological examination showed that the tumor was pleural amyloidosis. The tumor was diagnosed as localized primary amyloidosis, because serum monoclonal protein concentration did not increase. Pleural amyloidosis should be considered as a differential diagnosis from pleural mesothelioma.
我们在此报告一名65岁无症状男性，患有类似恶性胸膜间皮瘤的局限性胸膜淀粉样变。他有石棉接触史，因胸部X线检查发现胸膜厚度异常而入院接受检查。正电子发射断层扫描显示与胸膜厚度相应的标准化摄取值升高。为明确诊断和控制局部疾病，进行了包括肿瘤在内的部分胸膜切除术。病理检查显示肿瘤为胸膜淀粉样变。由于血清单克隆蛋白浓度未升高，该肿瘤被诊断为局限性原发性淀粉样变。胸膜淀粉样变应作为胸膜间皮瘤的鉴别诊断之一。
