Alkan Ali, Karcı Ebru, Yaşar Arzu, Tuncay Gülseren, Köksoy Elif Berna, Ürün Muslih, Şenler Filiz Çay, Demirkazık Ahmet, Utkan Güngör, Akbulut Hakan, Ürün Yüksel
Medical Oncology, Ankara University School of Medicine, Ankara, Turkey.
Internal Medicine, Ankara University School of Medicine, Ankara, Turkey.
Support Care Cancer. 2017 Sep;25(9):2677-2682. doi: 10.1007/s00520-017-3675-y. Epub 2017 Mar 22.
Despite, vaccination is a highly effective and widely recommended for prevention of certain infections, vaccination coverage is very low. The purposes of this study were to evaluate the attitudes of medical oncologists towards vaccination and to identify predictors of intention to recommend vaccination in patients with cancer.
A structured questionnaire is formed to evaluate the daily practice of vaccination. Turkish medical oncologists were invited to this study via email, SMS, or phone call. Questionnaire was filled out and the data were stored in an online survey platform.
Two hundred seventy-three medical oncologists participated in the survey. Influenza, Pneumococcus, and hepatitis B were the most commonly recommended vaccines (87.1, 72.8, 67.0%, respectively). Patients with lung cancer, lymphoma and breast cancer were the main malignancies that medical oncologists suggest vaccination (68.1, 68.1, 24.6%, respectively). The most common times for vaccination were during remission/follow-up period (68.4%) or before beginning chemotherapy (64.1%). Only 23.4% of the physicians thought that their recommendation for vaccination was efficient and adequate. Lack of time and lack of knowledge or experience about vaccination are the most common limitations. There is a positive correlation between experience in the field and evaluating patients for vaccination (r = 0.390, p < 0.001); on the other hand, there is negative correlation between number of patients seen per day and evaluating patients for vaccination (r = -0.080, p = 0.18). Experience with autologous or allogeneic bone marrow transplant patients is related with more tendency to evaluate patients for vaccination (p < 0.001).
Degree of experience in oncology especially in bone marrow transplant units and total number of patients seen per day are important predictors of vaccination practice in oncology. The frequency of recommendation increases with degree of experience, knowledge, and visit time per patient.
尽管疫苗接种是预防某些感染的一种非常有效的方法且被广泛推荐，但疫苗接种覆盖率却很低。本研究的目的是评估肿瘤内科医生对疫苗接种的态度，并确定癌症患者中推荐疫苗接种意愿的预测因素。
编制一份结构化问卷以评估疫苗接种的日常实践情况。通过电子邮件、短信或电话邀请土耳其肿瘤内科医生参与本研究。问卷填写完成后，数据存储在一个在线调查平台上。
273名肿瘤内科医生参与了此次调查。流感疫苗、肺炎球菌疫苗和乙肝疫苗是最常被推荐的疫苗（分别为87.1%、72.8%、67.0%）。肺癌、淋巴瘤和乳腺癌患者是肿瘤内科医生建议接种疫苗的主要恶性肿瘤患者群体（分别为68.1%、68.1%、24.6%）。最常见的接种时间是缓解期/随访期（68.4%）或开始化疗前（64.1%）。只有23.4%的医生认为他们对疫苗接种的推荐是有效且充分的。时间不足以及缺乏关于疫苗接种的知识或经验是最常见的限制因素。该领域的经验与对患者进行疫苗接种评估之间存在正相关（r = 0.390，p < 0.001）；另一方面，每天看诊的患者数量与对患者进行疫苗接种评估之间存在负相关（r = -0.080，p = 0.18）。有自体或异体骨髓移植患者的诊疗经验与更倾向于对患者进行疫苗接种评估相关（p < 0.001）。
肿瘤学领域的经验程度，尤其是在骨髓移植科室的经验，以及每天看诊患者的总数，是肿瘤学中疫苗接种实践的重要预测因素。推荐频率随着经验程度、知识水平和每位患者的就诊时间而增加。
