Shen Yao, Zhao WeiXiu, Lin JianHua, Liu FangSun
Department of Obstetrics and Gynecology, Renji Hospital, School of Medicine, Shanghai Jiao Tong University, No. 160, Pujian Road, Shanghai, 200127, China.
J Clin Ultrasound. 2017 Oct;45(8):465-471. doi: 10.1002/jcu.22463. Epub 2017 Mar 23.
To compare the sonographic-estimated fetal weights (EFW) calculated with the Hadlock formula and with the Woo formula in a group of Chinese pregnant women.
We prospectively recruited term pregnancies for sonographic biometric examination. EFWs were calculated according to two formulas and compared with the corresponding birth weight (BW). We also assessed the sensitivity, specificity, positive predictive value (PPV), and negative predictive value (NPV) of EFW for the diagnosis of small-for-gestational age (SGA) and large-for-gestational age (LGA) neonates.
A total of 374 subjects who delivered within 7 days after the sonographic examinations was recruited. Using the Hadlock formula, the median absolute difference between EFW and BW was 182 g (15-308 g) and the median percentage difference was 5.3% (0.5-9.1%), whereas it was 230 g (62-367) and 7.1% (2.1-10.4%) for the Woo formula (p < 0.001). Several factors, namely the fetal presentation, gender, and high amniotic quantity, showed no evident impact on this predictive difference. Among the 175 women who delivered within 2 days after ultrasound, the sensitivity and specificity of Hadlock EFW were 100% and 97.1% for the detection of SGA and 48.1% and 97.3% for the detection of LGA, respectively. The PPV and NPV were 44.4% and 100.0% for the detection of SGA and 76.5% and 91.1% for the detection of LGA, respectively.
EFWs calculated using the Hadlock formula for our research subjects were as accurate as those reported for other populations. The predictive performance showed a high NPV for the diagnosis of SGA and a relatively acceptable PPV for the diagnosis of LGA. © 2017 Wiley Periodicals, Inc. J Clin Ultrasound 45:465-471, 2017.
比较在中国孕妇群体中使用哈德洛克公式和吴公式计算的超声估计胎儿体重（EFW）。
我们前瞻性招募足月妊娠孕妇进行超声生物测量检查。根据两个公式计算EFW，并与相应的出生体重（BW）进行比较。我们还评估了EFW诊断小于胎龄儿（SGA）和大于胎龄儿（LGA）新生儿的敏感性、特异性、阳性预测值（PPV）和阴性预测值（NPV）。
共招募了374名在超声检查后7天内分娩的受试者。使用哈德洛克公式时，EFW与BW之间的中位绝对差值为182 g（15 - 308 g），中位百分比差值为5.3%（0.5 - 9.1%）；而使用吴公式时，中位绝对差值为230 g（62 - 367），中位百分比差值为7.1%（2.1 - 10.4%）（p < 0.001）。胎儿先露、性别和羊水过多等几个因素对这种预测差异无明显影响。在超声检查后2天内分娩的175名女性中，哈德洛克EFW检测SGA的敏感性和特异性分别为100%和97.1%，检测LGA的敏感性和特异性分别为48.1%和97.3%。检测SGA的PPV和NPV分别为44.4%和100.0%，检测LGA的PPV和NPV分别为76.5%和91.1%。
在我们的研究对象中，使用哈德洛克公式计算的EFW与其他人群报道的一样准确。预测性能显示，诊断SGA时NPV较高，诊断LGA时PPV相对可接受。© 2017威利期刊公司。《临床超声杂志》2017年第45卷第465 - 471页。
