Min Gee Ho, Kim Young, Lee Jong Seok, Oh Jee Youn, Hur Gyu Young, Lee Young Seok, Min Kyung Hoon, Lee Sung Yong, Kim Je Hyeong, Shin Chol, Lee Seung Heon
Division of Pulmonary, Sleep, and Critical Care Medicine, Department of Internal Medicine, Korea University Ansan Hospital, Korea University College of Medicine, Ansan, Korea.
Division of Pulmonary, Sleep, and Critical Care Medicine, Department of Internal Medicine, Korea University Guro Hospital, Korea University College of Medicine, Seoul, Korea.
Yonsei Med J. 2017 May;58(3):592-597. doi: 10.3349/ymj.2017.58.3.592.
To determine the social and clinical characteristics of immigrants with tuberculosis (TB) in South Korea.
The registered adult TB patients who were diagnosed and treated in Korea Medical Centers from January 2013 to December 2015 were analyzed retrospectively. A total of 105 immigrants with TB were compared to 932 native Korean TB patients.
Among these 105 immigrants with TB, 86 (82%) were Korean-Chinese. The rate of drug-susceptible TB were lower in the immigrants group than in the native Korean group [odds ratio (OR): 0.46; 95% confidence interval (CI): 0.22-0.96, p=0.035]. Cure rate was higher in the immigrant group than in the native Korean group (OR: 2.03; 95% CI: 1.26-3.28, p=0.003). Treatment completion rate was lower in the immigrant group than in the native Korean group (OR: 0.50; 95% CI: 0.33-0.74, p=0.001). However, treatment success rate showed no significant difference between two groups (p=0.141). Lost to follow up (default) rate was higher in the immigrant group than in the native Korean group after adjusting for age and drug resistance (OR: 3.61; 95% CI: 1.36-9.61, p=0.010). There was no difference between defaulter and non-defaulter in clinical characteristics or types of visa among these immigrants (null p value). However, 43 TB patients with recent immigration were diagnosed as TB even though they had been screened as normal at the time of immigration.
Endeavor to reduce the default rate of immigrants with TB and reinforce TB screening during the immigration process must be performed for TB infection control in South Korea.
确定韩国结核病(TB)移民的社会和临床特征。
回顾性分析2013年1月至2015年12月在韩国医疗中心诊断和治疗的成年登记结核病患者。将105例结核病移民患者与932例韩国本土结核病患者进行比较。
在这105例结核病移民中,86例(82%)是韩裔中国人。移民组药物敏感结核病的发生率低于韩国本土组[比值比(OR):0.46;95%置信区间(CI):0.22 - 0.96,p = 0.035]。移民组的治愈率高于韩国本土组(OR:2.03;95% CI:1.26 - 3.28,p = 0.003)。移民组的治疗完成率低于韩国本土组(OR:0.50;95% CI:0.33 - 0.74,p = 0.001)。然而,两组的治疗成功率无显著差异(p = 0.141)。在调整年龄和耐药性后,移民组失访(违约)率高于韩国本土组(OR:3.61;95% CI:1.36 - 9.61,p = 0.010)。这些移民中,违约者和非违约者在临床特征或签证类型方面没有差异(p值无意义)。然而,43例近期移民的结核病患者在移民时筛查正常,但后来被诊断为结核病。
为控制韩国的结核病感染,必须努力降低结核病移民的违约率,并在移民过程中加强结核病筛查。