Department of Urology, University Medical Center Goettingen, 37075 Goettingen, Germany.
Harvard T.H. Chan School of Public Health, Boston, MA 02115, USA.
J Public Health (Oxf). 2018 Mar 1;40(1):129-137. doi: 10.1093/pubmed/fdx030.
Studies have been published showing both increased and decreased utilization of cancer screening services in cancer survivors compared with cancer-free counterparts. This study synthesizes existing evidence in a meta-analysis.
A systematic literature review was conducted in August 2016. Studies were included if they compared the utilization of screening services for cervical, breast and colorectal cancer among adulthood cancer survivors to cancer-free controls. Random effects meta-analyses were conducted to pool estimates.
Of 3538 studies, 19 fulfilled the inclusion criteria. Cancer survivors were more likely to utilize screening services for breast cancer (odds ratio (OR) = 1.27, 95% confidence interval (CI): 1.13-1.42, P < 0.001), colorectal cancer (OR = 1.25, 95% CI: 1.15-1.37, P < 0.001) and cervical cancer (OR = 1.38, 95% CI: 1.08-1.75, P < 0.001) than cancer-free controls.
Overall, cancer survivors were more likely to utilize cancer screening services when compared with cancer-free controls. Future studies should evaluate, whether the utilization of screening services translates into prolonged survival.
已有研究表明,癌症幸存者的癌症筛查服务利用率与无癌症对照相比既有增加也有减少。本研究通过荟萃分析综合了现有证据。
我们于 2016 年 8 月进行了系统的文献回顾。如果研究比较了成年癌症幸存者与无癌症对照者的宫颈癌、乳腺癌和结直肠癌筛查服务的利用情况,则将其纳入研究。采用随机效应荟萃分析来汇总估计值。
在 3538 项研究中,有 19 项符合纳入标准。与无癌症对照者相比,癌症幸存者更有可能利用乳腺癌(比值比 (OR) = 1.27,95%置信区间 (CI):1.13-1.42,P < 0.001)、结直肠癌(OR = 1.25,95% CI:1.15-1.37,P < 0.001)和宫颈癌(OR = 1.38,95% CI:1.08-1.75,P < 0.001)的筛查服务。
总体而言,与无癌症对照者相比,癌症幸存者更有可能利用癌症筛查服务。未来的研究应评估筛查服务的利用是否转化为更长的生存时间。