Chung Ren-Jei, Wang An-Ni, Liao Qing-Liang, Chuang Kai-Yu
Department of Chemical Engineering and Biotechnology, National Taipei University of Technology (Taipei Tech), Taipei 10608, Taiwan.
Department of Materials Physics, State Key Laboratory for Advanced Metals and Materials, University of Science and Technology Beijing, Beijing 100083, China.
Nanomaterials (Basel). 2017 Feb 10;7(2):36. doi: 10.3390/nano7020036.
Nowadays glucose detection is of great importance in the fields of biological, environmental, and clinical analyzes. In this research, we report a zinc oxide (ZnO) nanorod powder surface-coated with carbon material for non-enzymatic glucose sensor applications through a hydrothermal process and chemical vapor deposition method. A series of tests, including crystallinity analysis, microstructure observation, and electrochemical property investigations were carried out. For the cyclic voltammetric (CV) glucose detection, the low detection limit of 1 mM with a linear range from 0.1 mM to 10 mM was attained. The sensitivity was 2.97 μA/cm²mM, which is the most optimized ever reported. With such good analytical performance from a simple process, it is believed that the nanocomposites composed of ZnO nanorod powder surface-coated with carbon material are promising for the development of cost-effective non-enzymatic electrochemical glucose biosensors with high sensitivity.
如今,葡萄糖检测在生物、环境和临床分析领域具有重要意义。在本研究中,我们报道了一种通过水热法和化学气相沉积法制备的、表面涂覆有碳材料的氧化锌(ZnO)纳米棒粉末,用于非酶葡萄糖传感器应用。进行了一系列测试,包括结晶度分析、微观结构观察和电化学性能研究。对于循环伏安法(CV)葡萄糖检测,实现了1 mM的低检测限,线性范围为0.1 mM至10 mM。灵敏度为2.97 μA/cm²mM,这是迄今报道的最优化结果。由于通过简单工艺获得了如此良好的分析性能,相信由表面涂覆有碳材料的ZnO纳米棒粉末组成的纳米复合材料在开发具有高灵敏度的经济高效非酶电化学葡萄糖生物传感器方面具有广阔前景。