Department of Biomedical Sciences, Humanitas University, via Manzoni, 113-20089, Rozzano, (Milan), Italy.
Radiotherapy and Radiosurgery Unit, Humanitas Clinical and Research Center, via Manzoni, 56-20089, Rozzano, (Milan), Italy.
Sci Rep. 2017 Mar 23;7(1):358. doi: 10.1038/s41598-017-00426-y.
Imaging with positron emission tomography (PET)/computed tomography (CT) is crucial in the management of cancer because of its value in tumor staging, response assessment, restaging, prognosis and treatment responsiveness prediction. In the last years, interest has grown in texture analysis which provides an "in-vivo" lesion characterization, and predictive information in several malignances including NSCLC; however several drawbacks and limitations affect these studies, especially because of lack of standardization in features calculation, definitions and methodology reporting. The present paper provides a comprehensive review of literature describing the state-of-the-art of FDG-PET/CT texture analysis in NSCLC, suggesting a proposal for harmonization of methodology.
正电子发射断层扫描（PET）/计算机断层扫描（CT）成像在癌症管理中至关重要，因为它在肿瘤分期、反应评估、重新分期、预后和治疗反应预测方面具有价值。近年来，人们对纹理分析越来越感兴趣，纹理分析为包括非小细胞肺癌（NSCLC）在内的几种恶性肿瘤提供了一种“体内”病变特征和预测信息；然而，这些研究存在一些缺点和局限性，尤其是由于缺乏特征计算、定义和方法报告的标准化。本文对描述 NSCLC 中 FDG-PET/CT 纹理分析的最新技术的文献进行了全面回顾，提出了一种方法学协调的建议。
