• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

首例经肛门内镜下肌切除术(PAEM):一种用于切除直肠严重纤维化病变的新型内镜技术。

First reported case of per anal endoscopic myectomy (PAEM): A novel endoscopic technique for resection of lesions with severe fibrosis in the rectum.

作者信息

Rahni David Ozzie, Toyonaga Takashi, Ohara Yoshiko, Lombardo Francesco, Baba Shinichi, Takihara Hiroshi, Tanaka Shinwa, Kawara Fumiaki, Azuma Takeshi

机构信息

Brown University/Rhode Island Hospital, Rhode Island Hospital, Providence, United States.

Department of Endoscopy, Kobe University Hospital, Kobe, Japan; Department of Endoscopy, Kishiwada Tokushukai Hospital, Kishiwada, Japan.

出版信息

Endosc Int Open. 2017 Mar;5(3):E146-E150. doi: 10.1055/s-0042-122965.

DOI:10.1055/s-0042-122965
PMID:28337484
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC5362086/
Abstract

A 54-year-old man was diagnosed with a rectal tumor extending through the submucosal layer. The patient refused surgery and therefore endoscopic submucosal dissection (ESD) was pursued. The lesion exhibited the muscle retraction sign After dissecting circumferentially around the fibrotic area by double tunneling method, a myotomy was performed through the internal circular muscle layer, creating a plane of dissection between the internal circular muscle layer and the external longitudinal muscle layer, and a myectomy was completed. The pathologic specimen verified T1b grade 1 sprouting adenocarcinoma with 4350 µm invasion into the submucosa with negative resection margins.

摘要

一名54岁男性被诊断为直肠肿瘤,肿瘤已穿透黏膜下层。患者拒绝手术,因此采用了内镜黏膜下剥离术(ESD)。病变表现出肌肉收缩征。通过双隧道法在纤维化区域周围进行环形剥离后,经内环肌层进行肌切开术,在内环肌层和外纵肌层之间形成一个剥离平面,完成了肌切除术。病理标本证实为T1b 1级芽生性腺癌,侵犯黏膜下层4350 µm,切缘阴性。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9352/5362086/09f248da45e4/10-1055-s-0042-122965-i654ei4.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9352/5362086/43b3f21add37/10-1055-s-0042-122965-i654ei1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9352/5362086/c79a8b080048/10-1055-s-0042-122965-i654ei2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9352/5362086/d9ed5bba8b11/10-1055-s-0042-122965-i654ei3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9352/5362086/09f248da45e4/10-1055-s-0042-122965-i654ei4.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9352/5362086/43b3f21add37/10-1055-s-0042-122965-i654ei1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9352/5362086/c79a8b080048/10-1055-s-0042-122965-i654ei2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9352/5362086/d9ed5bba8b11/10-1055-s-0042-122965-i654ei3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9352/5362086/09f248da45e4/10-1055-s-0042-122965-i654ei4.jpg

相似文献

1
First reported case of per anal endoscopic myectomy (PAEM): A novel endoscopic technique for resection of lesions with severe fibrosis in the rectum.首例经肛门内镜下肌切除术(PAEM):一种用于切除直肠严重纤维化病变的新型内镜技术。
Endosc Int Open. 2017 Mar;5(3):E146-E150. doi: 10.1055/s-0042-122965.
2
Peranal endoscopic myectomy (PAEM) for rectal lesions with severe fibrosis and exhibiting the muscle-retracting sign.经肛门内镜下肌切除术(PAEM)治疗伴有严重纤维化并出现肌肉退缩征的直肠病变。
Endoscopy. 2018 Aug;50(8):813-817. doi: 10.1055/a-0602-3905. Epub 2018 Jun 8.
3
Two Cases of Rectal Neuroendocrine Tumor Resection Combined with Dissection of the Circular Muscle Layer Using the Endoscopic Submucosal Dissection Technique.内镜黏膜下剥离术治疗直肠神经内分泌肿瘤并环形肌层剥离2例
Case Rep Gastroenterol. 2016 Nov 21;10(3):693-700. doi: 10.1159/000452758. eCollection 2016 Sep-Dec.
4
AGA Institute Clinical Practice Update: Endoscopic Submucosal Dissection in the United States.AGA 研究所临床实践更新:美国内镜黏膜下剥离术。
Clin Gastroenterol Hepatol. 2019 Jan;17(1):16-25.e1. doi: 10.1016/j.cgh.2018.07.041. Epub 2018 Aug 2.
5
[Clinical short-term and long-term efficacy of endoscopic submucosal dissection in the treatment of early low rectal cancer and precancerous lesions].内镜黏膜下剥离术治疗早期低位直肠癌及癌前病变的临床短期和长期疗效
Zhonghua Wei Chang Wai Ke Za Zhi. 2019 Jul 25;22(7):639-642. doi: 10.3760/cma.j.issn.1671-0274.2019.07.007.
6
[Application of dental floss traction-assisted endoscopic submucosa dissection to rectal neuroendocrine neoplasm].牙线牵引辅助内镜黏膜下剥离术在直肠神经内分泌肿瘤中的应用
Zhonghua Wei Chang Wai Ke Za Zhi. 2019 Apr 25;22(4):377-382. doi: 10.3760/cma.j.issn.1671-0274.2019.04.011.
7
Endoscopic submucosal dissection as excisional biopsy for anorectal malignant melanoma: A case report.内镜下黏膜下剥离术作为肛管直肠恶性黑色素瘤的切除活检:病例报告
World J Clin Cases. 2019 Jul 6;7(13):1652-1659. doi: 10.12998/wjcc.v7.i13.1652.
8
[Endoscopic submucosal dissection for rectal carcinoid tumors].[直肠类癌肿瘤的内镜黏膜下剥离术]
Zhonghua Wei Chang Wai Ke Za Zhi. 2007 Jul;10(4):319-22.
9
Endoscopic submucosal dissection and endoscopic mucosal resection for early stage esophageal cancer.早期食管癌的内镜黏膜下剥离术和内镜黏膜切除术
Ann Cardiothorac Surg. 2017 Mar;6(2):88-98. doi: 10.21037/acs.2017.03.15.
10
Novel technique of endoscopic submucosal dissection by using external forceps for early rectal cancer (with videos).利用外部夹具进行内镜黏膜下剥离术治疗早期直肠癌的新方法(附视频)。
Gastrointest Endosc. 2012 Jun;75(6):1253-7. doi: 10.1016/j.gie.2012.02.018.

引用本文的文献

1
Dissection of giant bulky colorectal lesions with muscle retracting sign (MRS+). Strategic management of gravitational traction during ESD might be the solution.采用肌肉收缩征(MRS+)切除巨大的结直肠病变。内镜黏膜下剥离术(ESD)期间重力牵引的策略性管理可能是解决办法。
Tech Coloproctol. 2025 May 27;29(1):124. doi: 10.1007/s10151-025-03151-1.
2
Feasibility of a novel slim gastroscope for endoscopic submucosal dissection: A case series (with video).新型细径胃镜用于内镜黏膜下剥离术的可行性:病例系列(附视频)
DEN Open. 2025 May 6;6(1):e70139. doi: 10.1002/deo2.70139. eCollection 2026 Apr.
3
Colitis-Associated Dysplasia in Inflammatory Bowel Disease: Features and Endoscopic Management.

本文引用的文献

1
Narrow-band imaging (NBI) magnifying endoscopic classification of colorectal tumors proposed by the Japan NBI Expert Team.日本窄带成像(NBI)专家组提出的结直肠肿瘤窄带成像(NBI)放大内镜分类。
Dig Endosc. 2016 Jul;28(5):526-33. doi: 10.1111/den.12644. Epub 2016 Apr 20.
2
Endoscopic submucosal dissection for anorectal tumor with hemorrhoids close to the dentate line: a multicenter study of Hiroshima GI Endoscopy Study Group.齿状线附近合并痔的肛肠肿瘤的内镜下黏膜下剥离术:广岛胃肠内镜研究组的多中心研究
Surg Endosc. 2016 Oct;30(10):4425-31. doi: 10.1007/s00464-016-4761-9. Epub 2016 Feb 19.
3
Risk of stricture after endoscopic submucosal dissection for large rectal neoplasms.
炎症性肠病中的结肠炎相关发育异常:特征与内镜管理
Cancers (Basel). 2025 Feb 25;17(5):784. doi: 10.3390/cancers17050784.
4
Sparse outer longitudinal muscle layer in peranal endoscopic myectomy: reinforcement of wound closure with peptide gel.经肛门内镜下肌切除术中外纵肌层稀疏:用肽凝胶加强伤口闭合
Endoscopy. 2024 Dec;56(S 01):E1052-E1053. doi: 10.1055/a-2467-3573. Epub 2024 Nov 29.
5
First report of gastric endoscopic intermuscular dissection.胃内镜肌间剥离术的首次报告。
Endoscopy. 2024 Dec;56(S 01):E132-E133. doi: 10.1055/a-2233-2914. Epub 2024 Mar 7.
6
Endoscopic intermuscular dissection (EID) for removing early rectal cancers and benign fibrotic rectal lesions.内镜下肌间分离术(EID)用于切除早期直肠癌和良性纤维性直肠病变。
Tech Coloproctol. 2023 Dec;27(12):1393-1400. doi: 10.1007/s10151-023-02862-7. Epub 2023 Sep 29.
7
Saline-tunneling endoscopic intermuscular dissection for the removal of rectal cancer using the hydrodissection method.使用水分离法经隧道注入生理盐水的内镜下肌间剥离术治疗直肠癌。
Endoscopy. 2023 Dec;55(S 01):E987-E989. doi: 10.1055/a-2142-4654. Epub 2023 Aug 21.
8
Endoscopic intermuscular dissection (EID) of a severely fibrotic benign rectal lesion in an area affected by radiation proctitis.在受放射性直肠炎影响的区域对严重纤维化的良性直肠病变进行内镜下肌层剥离术(EID)。
Endosc Int Open. 2023 Aug 7;11(8):E733-E734. doi: 10.1055/a-2109-8166. eCollection 2023 Aug.
9
Endoscopic intermuscular dissection with intermuscular tunneling for local resection of rectal cancer with deep submucosal invasion.内镜下肌间剥离联合肌间隧道技术用于局部切除伴有深层黏膜下浸润的直肠癌。
VideoGIE. 2022 Apr 17;7(8):273-277. doi: 10.1016/j.vgie.2022.02.012. eCollection 2022 Aug.
10
The pocket-creation method may facilitate endoscopic submucosal dissection of large colorectal sessile tumors.袋状创建法可能有助于大肠大型无蒂肿瘤的内镜黏膜下剥离术。
Endosc Int Open. 2020 Aug;8(8):E1021-E1030. doi: 10.1055/a-1190-7880. Epub 2020 Jul 21.
大肠巨大肿瘤内镜黏膜下剥离术后的狭窄风险。
Endoscopy. 2016 Jan;48(1):62-70. doi: 10.1055/s-0034-1392514. Epub 2015 Jul 28.
4
Clinical significance of the muscle-retracting sign during colorectal endoscopic submucosal dissection.结直肠内镜黏膜下剥离术中肌肉收缩征的临床意义
Endosc Int Open. 2015 Jun;3(3):E246-51. doi: 10.1055/s-0034-1391665. Epub 2015 May 5.
5
Pocket-creation method of endoscopic submucosal dissection to achieve en bloc resection of giant colorectal subpedunculated neoplastic lesions.内镜黏膜下剥离术的袋状创建方法,以实现大肠巨大亚蒂性肿瘤性病变的整块切除。
Endoscopy. 2014;46 Suppl 1 UCTN:E421-2. doi: 10.1055/s-0034-1377438. Epub 2014 Oct 14.
6
Factors associated with risk for colorectal cancer recurrence after endoscopic resection of T1 tumors.内镜切除 T1 肿瘤后结直肠癌复发风险的相关因素。
Clin Gastroenterol Hepatol. 2014 Feb;12(2):292-302.e3. doi: 10.1016/j.cgh.2013.08.008. Epub 2013 Aug 17.
7
Long-term outcomes after resection for submucosal invasive colorectal cancers.黏膜下浸润性结直肠肿瘤切除术后的长期预后。
Gastroenterology. 2013 Mar;144(3):551-9; quiz e14. doi: 10.1053/j.gastro.2012.12.003. Epub 2012 Dec 8.
8
Submucosal endoscopic tumor resection for subepithelial tumors in the esophagus and cardia.黏膜下内镜肿瘤切除术治疗食管和贲门部黏膜下肿瘤。
Endoscopy. 2012 Mar;44(3):225-30. doi: 10.1055/s-0031-1291659. Epub 2012 Feb 21.
9
Transanal endoscopic microsurgery is superior to transanal excision of rectal adenomas.经肛门内镜微创手术优于经肛门切除直肠腺瘤。
Colorectal Dis. 2011 Jul;13(7):762-7. doi: 10.1111/j.1463-1318.2010.02269.x. Epub 2010 Mar 23.
10
Submucosal endoscopy with mucosal flap safety valve.带黏膜瓣安全阀的黏膜下内镜检查
Gastrointest Endosc. 2007 Apr;65(4):688-94. doi: 10.1016/j.gie.2006.07.030. Epub 2007 Feb 26.