• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

内镜下肌间分离术(EID)用于切除早期直肠癌和良性纤维性直肠病变。

Endoscopic intermuscular dissection (EID) for removing early rectal cancers and benign fibrotic rectal lesions.

机构信息

Gastroenterology Department, General Hospital of Nikaia - Piraeus "Agios Panteleimon", Mantouvalou D.3, Nikaia, 18454, Athens, Greece.

Department of Gastroenterology and Hepatology, Kindai University, Osaka, Japan.

出版信息

Tech Coloproctol. 2023 Dec;27(12):1393-1400. doi: 10.1007/s10151-023-02862-7. Epub 2023 Sep 29.

DOI:10.1007/s10151-023-02862-7
PMID:37773471
Abstract

In the current era of screening colonoscopy and increasing incidence of early rectal cancer, interventional endoscopy moves toward resections in deeper planes than the submucosal layer. Several reports support the use of endoscopic intermuscular dissection (EID) instead of endoscopic submucosal dissection (ESD) for the removal of deeply invasive rectal submucosal cancers. The resection plane into the intermuscular space, the space between the longitudinal (external) and circular (internal) muscle layer, allows radical removal of rectal invasive submucosal cancers. Furthermore, the technique offers the potential for dissection of scarred and severe fibrotic lesions in the rectum by cutting deeper and performing a partial myectomy avoiding the narrow submucosal space. We present 23 cases of EIDs both for deeply invasive rectal cancers and benign rectal lesions. This is the first report in the literature of EID resections for malignant and benign disease, including cases of severely fibrotic rectal lesions.

摘要

在当前的结肠镜筛查和早期直肠癌发病率增加的时代,介入内镜的手术部位已深入到黏膜下层以外的层次。有几项研究报告支持使用内镜肌间分离术(EID)代替内镜黏膜下剥离术(ESD)来切除深度浸润性直肠黏膜下癌。该手术的切除平面位于肌间,即纵行(外)和环形(内)肌层之间的空间,可彻底切除直肠浸润性黏膜下癌。此外,该技术还可以通过更深的切割和部分肌切除术来分离直肠中瘢痕和严重纤维化病变,从而避免狭窄的黏膜下空间。我们报告了 23 例 EID 治疗深度浸润性直肠癌和良性直肠病变的病例。这是文献中首次报道 EID 用于治疗恶性和良性疾病的病例,包括严重纤维化的直肠病变。

相似文献

1
Endoscopic intermuscular dissection (EID) for removing early rectal cancers and benign fibrotic rectal lesions.内镜下肌间分离术(EID)用于切除早期直肠癌和良性纤维性直肠病变。
Tech Coloproctol. 2023 Dec;27(12):1393-1400. doi: 10.1007/s10151-023-02862-7. Epub 2023 Sep 29.
2
[Report on the application of endoscopic intermuscular dissection for diagnostic resection of early rectal cancer].[内镜下肌层剥离术在早期直肠癌诊断性切除中的应用报告]
Zhonghua Wei Chang Wai Ke Za Zhi. 2024 Jun 25;27(6):630-633. doi: 10.3760/cma.j.cn441530-20240314-00098.
3
Endoscopic intermuscular dissection for deep submucosal invasive cancer in the rectum: a new endoscopic approach.直肠深部黏膜下浸润性癌的内镜肌间分离术:一种新的内镜方法。
Endoscopy. 2022 Oct;54(10):993-998. doi: 10.1055/a-1748-8573. Epub 2022 Jan 24.
4
Endoscopic submucosal dissection in rectal tumors extending or not to the dentate line: A comparative analysis.直肠肿瘤内镜黏膜下剥离术:延伸至或不延伸至齿状线的比较分析。
Dig Liver Dis. 2020 Mar;52(3):296-300. doi: 10.1016/j.dld.2019.10.009. Epub 2019 Nov 17.
5
Stenosis rates after endoscopic submucosal dissection of large rectal tumors involving greater than three quarters of the luminal circumference.内镜下黏膜下剥离术治疗累及管腔周径超过四分之三的大型直肠肿瘤后的狭窄率。
Surg Endosc. 2016 Dec;30(12):5459-5464. doi: 10.1007/s00464-016-4906-x. Epub 2016 Apr 28.
6
AGA Institute Clinical Practice Update: Endoscopic Submucosal Dissection in the United States.AGA 研究所临床实践更新:美国内镜黏膜下剥离术。
Clin Gastroenterol Hepatol. 2019 Jan;17(1):16-25.e1. doi: 10.1016/j.cgh.2018.07.041. Epub 2018 Aug 2.
7
[A comparison of colonoscopy - assisted transanal minimally invasive surgery via glove port and endoscopic submucosal dissection in the treatment of early rectal tumors].[经手套端口结肠镜辅助经肛门微创手术与内镜黏膜下剥离术治疗早期直肠肿瘤的比较]
Zhonghua Wei Chang Wai Ke Za Zhi. 2019 Jul 25;22(7):656-661. doi: 10.3760/cma.j.issn.1671-0274.2019.07.010.
8
Wide-field endoscopic mucosal resection versus endoscopic submucosal dissection for laterally spreading colorectal lesions: a cost-effectiveness analysis.宽视野内镜下黏膜切除术与内镜黏膜下剥离术治疗结直肠侧向发育型肿瘤的成本效果分析。
Gut. 2018 Nov;67(11):1965-1973. doi: 10.1136/gutjnl-2017-313823. Epub 2017 Oct 7.
9
A colonoscopic overtube system that creates a 'therapeutic zone' and permits retraction facilitates endoscopic submucosal dissection, was associated with fewer deep bowel wall injuries and instrument exchanges, and required less lifting solution vs classic endoscopic submucosal dissection in an ex vivo bovine model.一种结肠镜外套管系统,可创建“治疗区”并允许回缩,从而有利于内镜黏膜下剥离术,与传统内镜黏膜下剥离术相比,在牛的离体模型中,这种方法与较少的深部肠壁损伤和器械交换相关,且需要更少的抬举溶液。
Surg Endosc. 2022 Aug;36(8):5897-5906. doi: 10.1007/s00464-022-09203-z. Epub 2022 Apr 11.
10
Circumferential rectal laterally spreading tumor resected by endoscopic submucosal dissection in a Western center.西方某中心经内镜黏膜下剥离术切除的环周直肠侧向发育型肿瘤
Endoscopy. 2017 Dec;49(12):E305-E306. doi: 10.1055/s-0043-119347. Epub 2017 Oct 9.

引用本文的文献

1
Efficacy of endoscopic intermuscular dissection vs. endoscopic submucosal dissection in treating rectal neuroendocrine tumors < 10 mm.内镜下肌层切开术与内镜下黏膜下剥离术治疗直径<10mm直肠神经内分泌肿瘤的疗效比较
Endosc Int Open. 2025 Aug 6;13:a26415725. doi: 10.1055/a-2641-5725. eCollection 2025.
2
Endoscopic Resection Techniques for Widespread Precancerous Lesions and Early Carcinomas in the Rectum.直肠广泛癌前病变和早期癌的内镜切除技术
J Clin Med. 2025 May 9;14(10):3322. doi: 10.3390/jcm14103322.
3
Dissection of giant bulky colorectal lesions with muscle retracting sign (MRS+). Strategic management of gravitational traction during ESD might be the solution.

本文引用的文献

1
Endoscopic Submucosal Dissection, Endoscopic Mucosal Resection, and Transanal Minimally Invasive Surgery for the Management of Rectal and Anorectal Lesions: A Narrative Review.内镜下黏膜下剥离术、内镜下黏膜切除术及经肛门微创手术治疗直肠和肛管病变:一项叙述性综述
J Clin Med. 2023 Jul 19;12(14):4777. doi: 10.3390/jcm12144777.
2
Per anal endoscopic myectomy for rectal neuroendocrine tumor invading submucosal deep layer and ending at the muscle layer.经肛门内镜下肌切除术治疗侵犯黏膜深层并止于肌层的直肠神经内分泌肿瘤。
Endoscopy. 2022 Dec;54(S 02):E858-E859. doi: 10.1055/a-1824-4732. Epub 2022 Jun 3.
3
Deep Submucosal Invasion Is Not an Independent Risk Factor for Lymph Node Metastasis in T1 Colorectal Cancer: A Meta-Analysis.
采用肌肉收缩征(MRS+)切除巨大的结直肠病变。内镜黏膜下剥离术(ESD)期间重力牵引的策略性管理可能是解决办法。
Tech Coloproctol. 2025 May 27;29(1):124. doi: 10.1007/s10151-025-03151-1.
4
Endoscopic approach to large non-pedunculated colorectal polyps.内镜下治疗大肠广基息肉的方法。
J Can Assoc Gastroenterol. 2025 Feb 21;8(Suppl 2):S62-S73. doi: 10.1093/jcag/gwae030. eCollection 2025 Mar.
5
Early Rectal Cancer and Local Excision: A Narrative Review.早期直肠癌与局部切除术:一篇叙述性综述
J Clin Med. 2024 Apr 16;13(8):2292. doi: 10.3390/jcm13082292.
6
[Endoscopic Resection Techniques for Precancerous and Early Cancerous Lesions in the Rectum].[直肠癌前病变和早期癌病变的内镜切除技术]
Zentralbl Chir. 2024 Feb;149(1):46-55. doi: 10.1055/a-2256-6724. Epub 2024 Mar 5.
深度黏膜下浸润不是 T1 结直肠癌淋巴结转移的独立危险因素:一项荟萃分析。
Gastroenterology. 2022 Jul;163(1):174-189. doi: 10.1053/j.gastro.2022.04.010. Epub 2022 Apr 15.
4
Endoscopic intermuscular dissection for deep submucosal invasive cancer in the rectum: a new endoscopic approach.直肠深部黏膜下浸润性癌的内镜肌间分离术:一种新的内镜方法。
Endoscopy. 2022 Oct;54(10):993-998. doi: 10.1055/a-1748-8573. Epub 2022 Jan 24.
5
Current problems and perspectives of pathological risk factors for lymph node metastasis in T1 colorectal cancer: Systematic review.当前 T1 结直肠癌淋巴结转移病理危险因素的问题与展望:系统综述。
Dig Endosc. 2022 Jul;34(5):901-912. doi: 10.1111/den.14220. Epub 2022 Jan 11.
6
Peranal endoscopic myectomy (PAEM) for rectal lesions with severe fibrosis and exhibiting the muscle-retracting sign.经肛门内镜下肌切除术(PAEM)治疗伴有严重纤维化并出现肌肉退缩征的直肠病变。
Endoscopy. 2018 Aug;50(8):813-817. doi: 10.1055/a-0602-3905. Epub 2018 Jun 8.
7
Does previous transanal excision for early rectal cancer impair surgical outcomes and pathologic findings of completion total mesorectal excision? Results of a systematic review of the literature.早期直肠癌先前经肛门切除术是否会影响根治性全直肠系膜切除术的手术效果及病理结果?文献系统评价结果
J Visc Surg. 2018 Dec;155(6):445-452. doi: 10.1016/j.jviscsurg.2018.03.008. Epub 2018 Apr 12.
8
Clinical outcomes of deep invasive submucosal colorectal cancer after ESD.内镜黏膜下剥离术治疗深度浸润性结直肠黏膜下肿瘤的临床疗效。
Surg Endosc. 2018 Apr;32(4):2123-2130. doi: 10.1007/s00464-017-5910-5. Epub 2017 Nov 2.
9
First reported case of per anal endoscopic myectomy (PAEM): A novel endoscopic technique for resection of lesions with severe fibrosis in the rectum.首例经肛门内镜下肌切除术(PAEM):一种用于切除直肠严重纤维化病变的新型内镜技术。
Endosc Int Open. 2017 Mar;5(3):E146-E150. doi: 10.1055/s-0042-122965.
10
Long-term clinical outcomes of endoscopic submucosal dissection for colorectal neoplasms in 423 cases: a retrospective study.423例大肠肿瘤内镜黏膜下剥离术的长期临床结局:一项回顾性研究
Endoscopy. 2017 Mar;49(3):233-242. doi: 10.1055/s-0042-124366. Epub 2017 Jan 20.