Bryja A, Dyszkiewicz-Konwińska M, Budna J, Kranc W, Chachuła A, Borys S, Ciesiółka S, Sokalski J, Prylinski M, Bukowska D, Antosik P, Bruska M, Nowicki M, Zabel M, Kempisty B
Department of Anatomy, Poznan University of Medical Sciences, Poznan, Poland.
Department of Biomaterials and Experimental Dentistry, Poznan University of Medical Sciences, Poznan, Poland.
J Biol Regul Homeost Agents. 2017 Jan-Mar;31(1):81-85.
In recent years, there has been a growing interest in epithelial cell tissue culture, particularly oral mucosa and its application utilizing in vitro cell culture in medicine. This involves tests using animal models to better understand oral mucosa function, and the differences in its construction in various animal models. The use of buccal pouch mucosal cell culture provides insight into the processes of trans mucosal transport and regeneration of the oral epithelium. The processes associated with epithelium regeneration is the base for stem cell research and/or oral cancer investigation. These artificially cultured tissue equivalents are used in transplant surgery for the treatment of a variety of tissue dysfunctions, i.e. eye, esophagus, or urethra. In this review, the most recent results from studies carried out on in animal models, which may be applied in areas such as regenerative medicine and reconstructive surgery, were explored.
近年来，人们对上皮细胞组织培养，尤其是口腔黏膜及其在医学体外细胞培养中的应用越来越感兴趣。这涉及使用动物模型进行测试，以更好地了解口腔黏膜功能，以及不同动物模型中其结构的差异。颊囊黏膜细胞培养的应用有助于深入了解跨黏膜运输和口腔上皮再生的过程。与上皮再生相关的过程是干细胞研究和/或口腔癌研究的基础。这些人工培养的组织等效物被用于移植手术，以治疗各种组织功能障碍，如眼睛、食道或尿道。在本综述中，探讨了在动物模型上进行的研究的最新结果，这些结果可能应用于再生医学和重建手术等领域。
