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急性后期疗养院入院期间的谵妄及不良后果风险

Delirium During Postacute Nursing Home Admission and Risk for Adverse Outcomes.

作者信息

Kosar Cyrus M, Thomas Kali S, Inouye Sharon K, Mor Vincent

机构信息

Center for Gerontology and Healthcare Research, Brown University, Providence, Rhode Island.

Department of Veteran Affairs Medical Center, Providence, Rhode Island.

出版信息

J Am Geriatr Soc. 2017 Jul;65(7):1470-1475. doi: 10.1111/jgs.14823. Epub 2017 Mar 24.

Abstract

OBJECTIVES

To identify the rate of delirium present during admission to postacute care (PAC) in the nursing home setting and to determine whether patients with delirium had higher risk for adverse outcomes.

DESIGN

Retrospective cohort study.

SETTING

US Medicare- and Medicaid-certified nursing homes, 2011 to 2014.

PARTICIPANTS

Individuals admitted to all US nursing homes for PAC, aged ≥65 years, and without prior history of nursing home residence (n = 5,588,702).

MEASUREMENTS

Minimum Data Set (MDS) 3.0 admission assessments identified delirium based upon Confusion Assessment Method (CAM) items. Robust Poisson regression was used to calculate adjusted relative risks (aRRs) with 95% confidence intervals (CIs) for death following PAC admission, and for 30-day discharge outcomes including re-hospitalization from PAC, discharge home, and functional improvement.

RESULTS

Delirium was identified in 4.3% of new postacute nursing home admissions. Mortality within 30 days of PAC admission was observed in 16.3% of patients with delirium and 5.8% of patients without delirium (aRR = 2.27, CI = 2.24-2.30). The rate of 30-day readmission from PAC was 21.3% for patients with delirium compared with 15.1% among patients without delirium (aRR = 1.42, 95% CI = 1.40, 1.43). 26.9% of patients with delirium were discharged home within 30 days of admission compared to 52.5% of patients without delirium (aRR = 0.57, 95% CI = 0.57, 0.58). 48.9% of patients with delirium showed functional improvement at discharge compared to 59.9% of patients without delirium (aRR = 0.83, 95% CI = 0.82, 0.83).

CONCLUSIONS

Patients with delirium present upon PAC admission were at high risk for mortality and 30-day re-hospitalization and were less likely to have timely discharge to home or to improve in physical function at discharge. Early identification and care planning for individuals with delirium at PAC admission may be essential to improve outcomes.

摘要

目的

确定在疗养院环境中入住急性后护理(PAC)期间谵妄的发生率,并确定谵妄患者是否有更高的不良结局风险。

设计

回顾性队列研究。

设置

2011年至2014年美国医疗保险和医疗补助认证的疗养院。

参与者

入住美国所有疗养院接受PAC的≥65岁个体,且无前疗养院居住史(n = 5,588,702)。

测量

最低数据集(MDS)3.0入院评估根据意识错乱评估方法(CAM)项目确定谵妄。稳健泊松回归用于计算PAC入院后死亡以及30天出院结局(包括从PAC再次住院、出院回家和功能改善)的调整相对风险(aRRs)及95%置信区间(CIs)。

结果

在新入住急性后护理疗养院的患者中,4.3%被确定为谵妄。PAC入院后30天内,谵妄患者的死亡率为16.3%,无谵妄患者为5.8%(aRR = 2.27,CI = 2.24 - 2.30)。谵妄患者从PAC 30天再入院率为21.3%,无谵妄患者为15.1%(aRR = 1.42,95%CI = 1.40,1.43)。26.9%的谵妄患者在入院30天内出院回家,无谵妄患者为52.5%(aRR = 0.57,95%CI = 0.57,0.58)。48.9%的谵妄患者出院时功能改善,无谵妄患者为59.9%(aRR = 0.83,95%CI = 0.82,0.83)。

结论

PAC入院时出现谵妄的患者有较高的死亡和30天再住院风险,且不太可能及时出院回家或出院时身体功能得到改善。对PAC入院时谵妄患者进行早期识别和护理规划可能对改善结局至关重要。

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