Warshaw Erin M, Hagen Solveig L, Belsito Donald V, DeKoven Joel G, Maibach Howard I, Mathias C G Toby, Zug Kathryn A, Sasseville Denis, Zirwas Matthew J, Fowler Joseph F, Fransway Anthony F, DeLeo Vincent A, Marks James G, Pratt Melanie D, Taylor James S
From the *HCMC Parkside Occupational and Contact Dermatitis Clinic and Department of Dermatology, Minneapolis Veterans Affairs Medical Center; and †Department of Dermatology, University of Minnesota Medical School, Minneapolis; ‡Department of Dermatology, Columbia University, New York, NY; §Division of Dermatology, Sunnybrook Health Sciences Centre, University of Toronto, Ontario, Canada; ∥Department of Dermatology, University of California San Francisco; ¶Department of Dermatology, University of Cincinnati, OH; #Dartmouth-Hitchcock Medical Center, Lebanon, NH; **Division of Dermatology, Royal Victoria Hospital, McGill University, Montreal, Quebec, Canada; ††Ohio State University, Columbus; ‡‡University of Louisville, KY; §§Associates in Dermatology, Fort Myers, FL; ∥∥Department of Dermatology, Keck School of Medicine at University of Southern California, Los Angeles; ¶¶Department of Dermatology, Pennsylvania State University, State College; ##Division of Dermatology, University of Ottawa, Ontario, Canada; and ***Department of Dermatology, Cleveland Clinic, OH.
Dermatitis. 2017 May/Jun;28(3):195-203. doi: 10.1097/DER.0000000000000269.
Little is known about the epidemiology of contact dermatitis (CD) in print machine operators (PMOs).
The aims of this study were to estimate the prevalence of CD and characterize clinically relevant and occupationally related allergens among PMOs undergoing patch testing.
This was a retrospective cross-sectional analysis of the North American Contact Dermatitis Group data from 1998 to 2014.
Of 39,332 patch-tested patients, 132 (0.3%) were PMOs. Among PMOs, most were male (75.0%) and white (92.4%). The majority were printing press operators (85.6%). The most frequent sites of dermatitis were hands (63.6%), arms (29.5%), and face/scalp (24.2%). More than half had an occupationally related skin condition (56.1%). Final diagnoses were most commonly allergic CD (58.3%) and irritant CD (33.3%). Cobalt (20.8%), carba mix (12.5%), thiuram mix (8.3%), and formaldehyde (8.3%) were the most frequent occupationally related allergens. The top allergen sources included inks (22.9%), gloves (20.8%), and coatings/dye/copy/photographic chemicals (14.6%).
Allergic CD, irritant CD, and involvement of exposed body areas were common among PMOs. Common allergens included rubber accelerators, metals, and preservatives.
对于印刷机操作员（PMO）中接触性皮炎（CD）的流行病学了解甚少。
本研究的目的是估计CD的患病率，并对接受斑贴试验的PMO中临床相关和职业相关的变应原进行特征描述。
这是一项对1998年至2014年北美接触性皮炎组数据的回顾性横断面分析。
在39332名接受斑贴试验的患者中，132名（0.3%）为PMO。在PMO中，大多数为男性（75.0%）和白人（92.4%）。大多数是印刷机操作员（85.6%）。皮炎最常见的部位是手部（63.6%）、手臂（29.5%）和面部/头皮（24.2%）。超过一半的人患有职业相关的皮肤病（56.1%）。最终诊断最常见的是过敏性CD（58.3%）和刺激性CD（33.3%）。钴（20.8%）、卡巴混合物（12.5%）、秋兰姆混合物（8.3%）和甲醛（8.3%）是最常见的职业相关变应原。最主要的变应原来源包括油墨（22.9%）、手套（20.8%）和涂料/染料/复印/照相化学品（14.6%）。
过敏性CD、刺激性CD以及暴露身体部位受累在PMO中很常见。常见的变应原包括橡胶促进剂、金属和防腐剂。
