DeKoven Joel G, DeKoven Benjamin M, Warshaw Erin M, Mathias C G T, Taylor James S, Sasseville Denis, Belsito Donald V, Fowler Joseph F, Pratt Melanie D, Zug Kathryn A, Maibach Howard I, DeLeo Vincent A, Silverberg Jonathan I, Atwater Amber R, Reeder Margo J, Holness D Linn
Division of Occupational Medicine, Department of Medicine, St Michael's Hospital, Unity Health, University of Toronto, Toronto, Ontario, Canada.
Division of Occupational Medicine, Department of Medicine, St Michael's Hospital, Unity Health, University of Toronto, Toronto, Ontario, Canada.
J Am Acad Dermatol. 2022 Apr;86(4):782-790. doi: 10.1016/j.jaad.2021.03.042. Epub 2021 Mar 19.
Patch testing is an important diagnostic tool for suspected allergic contact dermatitis (ACD) in occupational settings.
Provide an overview of occupational skin disease (OSD) and an analysis of occupational ACD in North American patients undergoing patch testing between 2001and 2016.
Patients with OSD were analyzed for frequency of allergic reactions to a screening series of allergens, occupational relevance, location of skin disease, and exposure sources. Demographic, occupation, and industry information were recorded.
Of 38,614 patients evaluated, 4471 (11.6%) had OSD, of whom 3150 (70.5%) had ACD. The most common occupationally related allergens included rubber accelerators, preservatives, and bisphenol A epoxy resin. Hands (75.8%), arms (30.0%), and face (15.9%) were common sites of dermatitis. The occupations most affected were service workers and machine operators.
Our cohort may not reflect the general working population.
This study identified common occupational allergens, exposure sources, and occupations/industries at risk. This information may help the clinician evaluate and manage patients with occupational contact dermatitis.
斑贴试验是职业环境中疑似过敏性接触性皮炎（ACD）的重要诊断工具。
概述职业性皮肤病（OSD），并分析2001年至2016年间接受斑贴试验的北美患者的职业性ACD。
分析OSD患者对一系列筛查变应原的过敏反应频率、职业相关性、皮肤病部位和暴露源。记录人口统计学、职业和行业信息。
在38614例接受评估的患者中，4471例（11.6%）患有OSD，其中3150例（70.5%）患有ACD。最常见的职业相关变应原包括橡胶促进剂、防腐剂和双酚A环氧树脂。手部（75.8%）、手臂（30.0%）和面部（15.9%）是皮炎的常见部位。受影响最严重的职业是服务人员和机器操作员。
我们的队列可能无法反映一般工作人群。
本研究确定了常见的职业变应原、暴露源以及有风险的职业/行业。这些信息可能有助于临床医生评估和管理职业性接触性皮炎患者。
