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Inactivation of dermatophyte infection by nonthermal plasma on animal model.

作者信息

Scholtz Vladimír, Soušková Hana, Švarcová Michaela, Kríha Vítezslav, Živná Helena, Julák Jaroslav

机构信息

Department of Physics and Measurements, University of Chemistry and Technology, Prague, Czech Republic.

Department of Computing and Control Engineering, University of Chemistry and Technology, Prague, Czech Republic.

出版信息

Med Mycol. 2017 Jun 1;55(4):422-428. doi: 10.1093/mmy/myw094.

DOI:10.1093/mmy/myw094
PMID:28339534
Abstract

Superficial fungal infections are a major epidemiological issue with increasing prevalence and are a common global problem. This article describes experimental therapy of superficial fungal skin infection using low-temperature plasma. Groups of guinea pigs were artificially infected with Trichophyton mentagrophytes SK 3286 dermatophyte and treated with plasma produced by a DC cometary discharge with an inserted grid. The course of infection was a week shorter and milder in animals treated by plasma than that in nontreated animals, the significant lowering of dermatophytic germs also occurred in the treated group. The exposure to plasma causes no harm to experimental animals. The results allow for the development of a new dermatophytoses therapy by low temperature plasma treatment.

摘要

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