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短链脂肪酸通过增加调节性T细胞来控制皮肤免疫反应。

SCFAs Control Skin Immune Responses via Increasing Tregs.

作者信息

Egawa Gyohei, Honda Tetsuya, Kabashima Kenji

机构信息

Department of Dermatology, Kyoto University Graduate School of Medicine, Kyoto, Japan.

Department of Dermatology, Kyoto University Graduate School of Medicine, Kyoto, Japan; Singapore Immunology Network (SIgN) and Institute of Medical Biology, Agency for Science, Technology and Research (A*STAR), Biopolis, Singapore; PRESTO, Japan Science and Technology Agency, Saitama, Japan.

出版信息

J Invest Dermatol. 2017 Apr;137(4):800-801. doi: 10.1016/j.jid.2016.12.022.

DOI:10.1016/j.jid.2016.12.022
PMID:28340682
Abstract

We are surrounded by billions of microbes, and our immune system is substantially affected by the commensal bacteria on the surface of our body. Schwarz et al. describe the immune-suppressive effect of sodium butyrate, a bacterial metabolite that is categorized as one of the short-chain fatty acids, during skin inflammatory responses.

摘要

我们周围存在着数十亿的微生物,我们的免疫系统受到体表共生细菌的显著影响。施瓦茨等人描述了丁酸钠(一种被归类为短链脂肪酸之一的细菌代谢产物)在皮肤炎症反应中的免疫抑制作用。

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