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[胃癌与消化性溃疡微量元素谱的模式识别]

[Pattern recognition on the trace element spectrum in gastric cancer and peptic ulcer].

作者信息

Liu Z X, Miao Q, Chen N Y, Shi K X, Xu L Z, Cheng W F, Guo X D, Yu Q X, Zhao Y X

机构信息

Shanghai Metallurgical Institute, Chinese Academy of Sciences.

出版信息

Zhonghua Zhong Liu Za Zhi. 1987 May;9(3):173-5.

PMID:2834156
Abstract

The trace element spectrum of gastric tissue and whole blood specimens from gastric cancer and peptic ulcer patients was recognized with pattern recognition technique in order to obtain the chemical information of gastric cancer. Thirty specimens were obtained from cancer patients in each of the 58 gastric tissues and 54 whole blood specimens. Five pathological types were divided into two groups: peptic ulcer and dysplasia as the ulcer group; well-differentiated, undifferentiated and mucinous carcinoma as the cancer group. The accuracy of recognizing the several spectra was 90%: nine trace element spectra (Cu, Zn, Ni, Co, Cr, Cd, Mn, Fe and Mg) for the tissue specimens from the cancer and ulcer groups; six (Cu, Zn, Mn, Co, Cr and Cd) for dysplasia and well-differentiated adenocarcinoma tissues; five (Cu, Ni, Cr, Cd and Fe) for the whole blood specimens from these two groups and six (Cu, Zn, Cr, Cd, Fe and Ni) for the whole blood specimens from dysplasia and peptic ulcer (including 10 normal individuals). The data were treated by non-linear mapping method and calculated by TRS-80 III type microcomputer.

摘要

为获取胃癌的化学信息,运用模式识别技术对胃癌患者及消化性溃疡患者的胃组织和全血标本中的微量元素谱进行识别。从58例胃组织和54例全血标本的癌症患者中各获取30个标本。将5种病理类型分为两组:消化性溃疡和发育异常归为溃疡组;高分化、未分化和黏液癌归为癌症组。识别几种光谱的准确率为90%:癌症组和溃疡组组织标本的9种微量元素谱(铜、锌、镍、钴、铬、镉、锰、铁和镁);发育异常和高分化腺癌组织的6种(铜、锌、锰、钴、铬和镉);这两组全血标本的5种(铜、镍、铬、镉和铁)以及发育异常和消化性溃疡(包括10名正常个体)全血标本的6种(铜、锌、铬、镉、铁和镍)。数据采用非线性映射法处理,并通过TRS - 80 III型微型计算机进行计算。

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