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膝关节和髋关节置换术结局的差异:ACS-NSQIP 临床注册观察性分析。

Disparities in Knee and Hip Arthroplasty Outcomes: an Observational Analysis of the ACS-NSQIP Clinical Registry.

机构信息

Department of Medicine, University of Toronto, 27 King's College Circle, Toronto, ON, M5S 1A1, Canada.

Division of General Internal Medicine, Sinai Health System and University Health Network, Toronto General Hospital, Eaton 14th Floor, 200 Elizabeth Street, Toronto, ON, M5G 2C4, Canada.

出版信息

J Racial Ethn Health Disparities. 2018 Feb;5(1):151-161. doi: 10.1007/s40615-017-0352-2. Epub 2017 Mar 24.

Abstract

BACKGROUND

Disparities in total joint arthroplasty (TJA) have largely been studied in single center studies and using administrative data. Our objective was to investigate differences in TJA outcomes in white men, black men, white women, and black women using a large international registry.

METHODS

We used 2010-2013 data from the ACS-NSQIP to identify four groups of adults (white men, black men, white women, black women) who underwent primary total knee arthroplasty (TKA) or total hip arthroplasty (THA). We compared differences in (1) surgical complications (mortality, pulmonary embolism, wound infection, sepsis, blood loss requiring transfusion, myocardial infarction, pneumonia, acute renal failure, and a composite representing occurrence of one or more adverse outcomes) and (2) discharge to a nursing home.

RESULTS

We identified 62,075 TKA and 39,334 THA patients. For TKA, 35.3% were white men, 57.2% white women, 1.9% black men, and 5.6% black women. White and black women were significantly more likely to experience our composite outcome when compared to their male counterparts (16.5 and 14.1% for white women and white men; P < .001) (18.3 and 14.3% for black women and black men; P = .002); higher complications for women were explained by higher transfusion rates in women (14.9 vs 12.2% for white women and men, 16.4 vs 11.7% for black; P < .001 for both). For TKA, blacks (compared to whites) and women (compared to men) were significantly more likely to be discharged to a nursing home. Results were similar for THA.

CONCLUSIONS

In contrast to prior studies, we found that complications after primary TJA were generally similar among white and black men and women with the exception of markedly higher transfusion rates among women of both racial groups.

摘要

背景

全关节置换术(TJA)的差异主要在单中心研究和使用行政数据中进行了研究。我们的目的是使用大型国际注册处调查白人男性、黑人男性、白人女性和黑人女性接受初次全膝关节置换术(TKA)或全髋关节置换术(THA)的 TJA 结果差异。

方法

我们使用 2010-2013 年 ACS-NSQIP 的数据确定了四组成年人(白人男性、黑人男性、白人女性、黑人女性),他们接受了初次全膝关节置换术(TKA)或全髋关节置换术(THA)。我们比较了(1)手术并发症(死亡率、肺栓塞、伤口感染、败血症、需要输血的失血、心肌梗死、肺炎、急性肾衰竭和代表一种或多种不良结局发生的复合结局)和(2)出院到疗养院的差异。

结果

我们确定了 62075 例 TKA 和 39334 例 THA 患者。对于 TKA,35.3%为白人男性,57.2%为白人女性,1.9%为黑人男性,5.6%为黑人女性。与男性相比,白人女性和黑人女性发生我们的复合结局的可能性明显更高(白人女性和白人男性为 16.5%和 14.1%;P<.001)(黑人女性和黑人男性为 18.3%和 14.3%;P=.002);女性并发症较高的原因是女性输血率较高(白人女性和男性为 14.9%和 12.2%,黑人女性和男性为 16.4%和 11.7%;均<.001)。对于 TKA,黑人(与白人相比)和女性(与男性相比)更有可能被送往疗养院。THA 的结果相似。

结论

与之前的研究不同,我们发现初次 TJA 后的并发症在白人男性和女性以及黑人和白人女性中总体相似,除了两个种族群体的女性输血率明显较高。

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