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首次发生产科肛门括约肌损伤(OASIS)后经阴道分娩时再次发生OASIS的发生率及危险因素:一项基于医院的队列研究。

The incidence of and risk factors for a repeat obstetric anal sphincter injury (OASIS) in the vaginal birth subsequent to a first episode of OASIS: a hospital-based cohort study.

作者信息

Antonakou Angeliki, Papoutsis Dimitrios, Henderson Karen, Qadri Zahid, Tapp Andrew

机构信息

Department of Obstetrics and Gynaecology, Shrewsbury and Telford Hospitals NHS Trust, Princess Royal Hospital, Apley Castle, Grainger Drive, Telford, TF16TF, UK.

出版信息

Arch Gynecol Obstet. 2017 May;295(5):1201-1209. doi: 10.1007/s00404-017-4352-6. Epub 2017 Mar 24.

Abstract

PURPOSE

To identify the incidence of and risk factors for a repeat obstetric anal sphincter injury (OASIS) in women who sustained an OASIS in their first vaginal delivery and have a subsequent vaginal birth.

METHODS

Data were collected retrospectively for women having had singleton cephalic presentation vaginal deliveries between 2007 and 2015. Women with breech deliveries, stillbirths, foetal congenital abnormalities and multiple pregnancies were excluded.

RESULTS

Over the study period, we identified 11,191 women who had a first vaginal birth, of which 603 (5.4%) sustained a first episode of OASIS. Of these women, 243 (40.2%) had a subsequent pregnancy with 190 (78.1%) having a second vaginal birth, 13 (5.4%) an emergency caesarean section (CS) delivery while in labour and 40 (16.5%) an elective CS delivery. In those who delivered vaginally, 16 (8.4%) women had a repeat OASIS. After adjusting for several confounding factors, it was found that the risk of a repeat OASIS was associated with the use of epidural analgesia (OR = 3.66; 95% CI: 1.14-11.71) and an episiotomy in the first delivery (OR = 3.93; 95% CI:1. 03-15.02) and a short labour (<2.8 h) in the second delivery (OR = 14.55; 95% CI: 1.83-115.75). The time interval between the two vaginal births was not associated with any increased risk of a repeat OASIS.

CONCLUSION

We found that 8.4% of women sustained a repeat OASIS in a subsequent vaginal birth with this risk being associated with the presence of a short second labour and certain features from the first labour.

摘要

目的

确定首次阴道分娩时发生产科肛门括约肌损伤(OASIS)且随后再次经阴道分娩的女性中再次发生OASIS的发生率及危险因素。

方法

回顾性收集2007年至2015年期间单胎头先露阴道分娩的女性数据。排除臀位分娩、死产、胎儿先天性异常及多胎妊娠的女性。

结果

在研究期间,我们确定了11191名首次经阴道分娩的女性,其中603名(5.4%)发生了首次OASIS。在这些女性中,243名(40.2%)再次怀孕,其中190名(78.1%)进行了第二次阴道分娩,13名(5.4%)在分娩时进行了急诊剖宫产(CS),40名(16.5%)进行了择期CS。在经阴道分娩的女性中,16名(8.4%)发生了再次OASIS。在对多个混杂因素进行校正后,发现再次发生OASIS的风险与使用硬膜外镇痛(OR = 3.66;95%CI:1.14 - 11.71)、首次分娩时行会阴切开术(OR = 3.93;95%CI:1.03 - 15.02)以及第二次分娩时产程短(<2.8小时)(OR = 14.55;95%CI:1.83 - 115.75)有关。两次阴道分娩之间的时间间隔与再次发生OASIS的风险增加无关。

结论

我们发现8.4%的女性在随后的阴道分娩中再次发生OASIS,这种风险与第二次产程短以及首次分娩的某些特征有关。

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