Department of Surgical Oncology, First Affiliated Hospital of Xi'an JiaoTong University, Xi'an, China.
Department of Surgical Oncology, First Affiliated Hospital of Xi'an JiaoTong University, Xi'an, China.
Int J Surg. 2017 Jun;42:183-190. doi: 10.1016/j.ijsu.2017.03.052. Epub 2017 Mar 23.
Compare the clinical outcome of Transhiatal Esophagectomy (THE) approach and open Thoracic Esophagectomy (TTE) approach in the carcinoma of esophagogastric junction (CEGJ).
Relevant literature published until 2016 from PubMed, Cochrane Library, Ovid (Medline) and EMBASE were retrieved. Meta-analysis was achieved by using the Stata12 software.
A total of 18 studies and 2202 cases of patients were involved in this meta-analysis. THE showed to decrease the hospital stay, hospital mortality, surgical time, and blood loss in the operation. However, fewer lymph nodes would be yielded by this surgical option. A 5-year survival advantage of THE was only observed in North America subgroup.
Except the above operative related advantages, there was no clear evidence that THE has a further advantage in CEGJ.
比较经食管裂孔食管癌切除术（THE）与开放性胸段食管癌切除术（TTE）治疗食管胃结合部癌（CEGJ）的临床效果。
检索 PubMed、Cochrane 图书馆、Ovid（Medline）和 EMBASE 数据库截至 2016 年发表的相关文献。采用 Stata12 软件进行 Meta 分析。
共纳入 18 项研究，2202 例患者。THE 可减少住院时间、住院死亡率、手术时间和术中出血量，但淋巴结清扫数目较少。THE 组仅在北美亚组中具有 5 年生存优势。
除了上述手术相关优势外，THE 治疗 CEGJ 并无明显优势。
