Kim Hye Jeong, Yoon Dae Young, Kim Eun Soo, Lee Hyung Jin, Jeon Hong Jun, Lee Jong Young, Cho Byung-Moon
Department of Radiology, Kangnam Sacred Heart Hospital, Hallym University College of Medicine, Seoul, South Korea.
Department of Radiology, Kangdong Seong-Sim Hospital, Hallym University College of Medicine, 150, Seongan-ro Gangdong-Gu, Seoul, 134-701, South Korea.
Neuroradiology. 2017 May;59(5):491-497. doi: 10.1007/s00234-017-1826-y. Epub 2017 Mar 25.
Accurate and reliable measurement of aneurysm size is important for treatment planning. The purpose of this study was to determine intraobserver and interobserver variability of CTA and MRA for measurement of the size of cerebral aneurysms.
Thirty patients with 33 unruptured cerebral aneurysms (saccular, >3 mm in their maximal dimension, with no daughter sacs or lobulations) who underwent 256-row multislice CTA, 3-D TOF MRA at 3.0T, and 3D rotational angiography (3DRA) were retrospectively analyzed. Three independent observers measured the neck, height, and width of the aneurysms using the CTA and MRA images. Intraobserver and interobserver variability of CTA and MRA measurements was evaluated using the standardized difference and intraclass correlation coefficient, with 3DRA measurements as the reference standard. In addition, the mean values of the measurements using CTA and MRA were compared with those using 3DRA.
The overall intraobserver and interobserver standardized differences in CTA/MRA were 12.83-15.92%/13.48-17.45% and 14.08-17.00%/12.08-17.67%, respectively. The overall intraobserver and interobserver intraclass correlation coefficients of CTA/MRA were 0.88-0.98/0.84-0.96 and 0.86-0.98/0.85-0.95, respectively. Compared to the height and width measurements, measurements of the neck dimensions showed higher intraobserver and interobserver variability. The sizes of the cerebral aneurysms measured by CTA and MRA were 1.13-9.26 and 5.20-9.67% larger than those measured by 3DRA, respectively; however, these differences were not statistically significant.
There were no noticeable differences between intraobserver and interobserver variability for both CTA- and MRA-based measurements of the size of cerebral aneurysms.
准确可靠地测量动脉瘤大小对于治疗方案的制定很重要。本研究的目的是确定CTA和MRA在测量脑动脉瘤大小时的观察者内及观察者间变异性。
回顾性分析30例患有33个未破裂脑动脉瘤（囊状，最大直径>3mm，无子囊或分叶）的患者，这些患者接受了256排多层CTA、3.0T的3D TOF MRA以及3D旋转血管造影（3DRA）检查。三名独立观察者使用CTA和MRA图像测量动脉瘤的颈部、高度和宽度。以3DRA测量值作为参考标准，使用标准化差异和组内相关系数评估CTA和MRA测量的观察者内及观察者间变异性。此外，将CTA和MRA测量的平均值与3DRA测量的平均值进行比较。
CTA/MRA的总体观察者内和观察者间标准化差异分别为12.83 - 15.92%/13.48 - 17.45%和14.08 - 17.00%/12.08 - 17.67%。CTA/MRA的总体观察者内和观察者间组内相关系数分别为0.88 - 0.98/0.84 - 0.96和0.86 - 0.98/0.85 - 0.95。与高度和宽度测量相比，颈部尺寸测量显示出更高的观察者内和观察者间变异性。CTA和MRA测量的脑动脉瘤大小分别比3DRA测量的大1.13 - 9.26%和5.20 - 9.67%；然而，这些差异无统计学意义。
基于CTA和MRA测量脑动脉瘤大小的观察者内和观察者间变异性没有明显差异。
