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对于减少单纯高能钝性创伤后的全身计算机断层扫描,临床判断并不可靠。

Clinical Judgment Is Not Reliable for Reducing Whole-body Computed Tomography Scanning after Isolated High-energy Blunt Trauma.

作者信息

Mistral Thomas, Brenckmann Vivien, Sanders Laurence, Bosson Jean-Luc, Ferretti Gilbert, Thony Frederic, Galvagno Samuel M, Payen Jean-François, Bouzat Pierre

机构信息

From the Grenoble Alpes Trauma Center, Pôle Anesthésie-Réanimation, CHU Grenoble Alpes, Grenoble, France (T.M., J-F.P., P.B.); Université Grenoble Alpes, Grenoble, France (T.M., V.B., J-L.B., G.F., J-F.P., P.B.); INSERM U1216, Grenoble, France (T.M., J-F.P., P.B.); Département de Médecine d'Urgence, CHU Grenoble Alpes, Grenoble, France (V.B., L.S.); Pôle Recherche, CHU Grenoble Alpes, Grenoble, France (J-L.B.); Pole Imagerie, CHU Grenoble Alpes, Grenoble, France (G.F., F.T.); Divisions of Trauma Anesthesiology and Critical Care Medicine, Department of Anesthesiology, R Adams Cowley Shock Trauma Center, Baltimore, Maryland (S.M.G.).

出版信息

Anesthesiology. 2017 Jun;126(6):1116-1124. doi: 10.1097/ALN.0000000000001617.

Abstract

BACKGROUND

The purpose of this study was to test the diagnostic performance of clinical judgment for the prediction of a significant injury with whole-body computed tomography scanning after high-energy trauma.

METHODS

The authors conducted an observational prospective study in a single level-I trauma center. Adult patients were included if they had an isolated high-energy injury. Senior trauma leaders were asked to make a clinical judgment regarding the likelihood of a significant injury before performance of a whole-body computed tomography scan. Clinical judgments were recorded using a probability diagnosis scale. The primary endpoint was the diagnosis of a serious-to-critical lesion on the whole-body computed tomography scan. Diagnostic performance was assessed using receiver operating characteristic analysis.

RESULTS

Of the 354 included patients, 127 patients (36%) had at least one injury classified as abbreviated injury score greater than or equal to 3. The area under the receiver operating characteristic curve of the clinical judgment to predict a serious-to-critical lesion was 0.70 (95% CI, 0.64 to 0.75%). The sensitivity of the clinical judgment was 82% (95% CI, 74 to 88%), and the specificity was 49% (95% CI, 42 to 55%). No patient with a strict negative clinical examination had a severe lesion (n = 19 patients). The sensitivity of the clinical examination was 100% (95% CI, 97 to 100%) and its specificity was 8% (95% CI, 5 to 13%).

CONCLUSIONS

Clinical judgment alone is not sufficient to reduce whole-body computed tomography scan use. In patients with a strictly normal physical examination, whole-body computed tomography scanning might be avoided, but this result deserves additional study in larger and more diverse populations of trauma patients.

摘要

背景

本研究旨在测试临床判断对高能创伤后全身计算机断层扫描预测严重损伤的诊断性能。

方法

作者在一家一级创伤中心进行了一项观察性前瞻性研究。纳入有孤立高能损伤的成年患者。在进行全身计算机断层扫描前,要求高级创伤负责人对严重损伤的可能性做出临床判断。使用概率诊断量表记录临床判断。主要终点是全身计算机断层扫描诊断出严重至危急病变。使用受试者工作特征分析评估诊断性能。

结果

在354例纳入患者中,127例患者(36%)至少有一处损伤分类为简明损伤定级大于或等于3级。临床判断预测严重至危急病变的受试者工作特征曲线下面积为0.70(95%可信区间,0.64至0.75%)。临床判断的敏感性为82%(95%可信区间,74至88%),特异性为49%(95%可信区间,42至55%)。临床检查严格阴性的患者均无严重病变(n = 19例患者)。临床检查的敏感性为100%(95%可信区间,97至100%),特异性为8%(95%可信区间,5至13%)。

结论

仅靠临床判断不足以减少全身计算机断层扫描的使用。对于体格检查严格正常的患者,可能可避免全身计算机断层扫描,但这一结果值得在更大、更多样化的创伤患者群体中进一步研究。

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