1999 - 2004年美国国家健康与营养检查调查（NHANES）四肢和躯干的双能X线吸收法身体成分参考值及其他可视化方法
Dual energy X-ray absorptiometry body composition reference values of limbs and trunk from NHANES 1999-2004 with additional visualization methods.
作者信息
Hinton Benjamin J, Fan Bo, Ng Bennett K, Shepherd John A
机构信息
Department of Radiology & Biomedical Imaging, University of California-San Francisco, San Francisco, California, United States of America.
Department of Bioengineering, University of California Berkeley and University of California San Francisco, San Francisco, California, United States of America.
出版信息
PLoS One. 2017 Mar 27;12(3):e0174180. doi: 10.1371/journal.pone.0174180. eCollection 2017.
Body Mass Index has traditionally been used as a measure of health, but Fat Mass Index (FMI) and Lean Mass Index (LMI) have been shown to be more predictive of mortality and health risk. Total body FMI and LMI reference curves have particularly been useful in quantifying sarcopenia and sarcopenic obesity. Research has shown regional composition has significant associations to health outcomes. We derived FMI and LMI reference curves of the regions of the body (leg, arm, and trunk) for 15,908 individuals in the 1999-2004 National Health and Nutrition Examination Survey data for each sex and ethnicity using the Lambda-Mu-Sigma (LMS) method and developed software to visualize this regional composition. These reference curves displayed differentiation between males and females during puberty and sharper limb LMI declines during late adulthood for males. For adults ages 30-50, females had 39%, 83%, and 47% larger arm, leg, and trunk FMI values than males, respectively. Males had 49%, 20%, and 15% higher regional LMI values than females for the arms, legs, and trunk respectively. The leg FMI and LMI of black females were 14% and 15% higher respectively than those of Hispanic and white females. White and Hispanic males had 37% higher trunk FMI values than black males. Hispanic females had 20% higher trunk FMI than white and black females. These data underscore the importance of accounting for sex and ethnicity in studies of regional composition. This study is the first to produce regional LMI and FMI reference tables and curves from the NHANES dataset. These reference curves provide a framework useful in studies and research involving sarcopenia, obesity, sarcopenic obesity, and other studies of compositional phenotypes. Further, the software tool we provide for visualizing regional composition will prove useful in monitoring progress in physical therapy, diets, or other attempts to attain healthier compositions.
体重指数传统上一直被用作健康指标，但脂肪量指数（FMI）和去脂体重指数（LMI）已被证明能更准确地预测死亡率和健康风险。全身FMI和LMI参考曲线在量化肌肉减少症和肌肉减少性肥胖方面特别有用。研究表明，身体各部位的组成与健康结果有显著关联。我们利用Lambda-Mu-Sigma（LMS）方法，从1999 - 2004年国家健康与营养检查调查数据中，为15908名不同性别和种族的个体得出了身体各部位（腿部、手臂和躯干）的FMI和LMI参考曲线，并开发了软件来可视化这种区域组成。这些参考曲线显示，青春期时男性和女性存在差异，成年后期男性四肢的LMI下降更为明显。对于30至50岁的成年人，女性手臂、腿部和躯干的FMI值分别比男性大39%、83%和47%。男性手臂、腿部和躯干的区域LMI值分别比女性高49%、20%和15%。黑人女性的腿部FMI和LMI分别比西班牙裔和白人女性高14%和15%。白人和西班牙裔男性的躯干FMI值比黑人男性高37%。西班牙裔女性的躯干FMI比白人和黑人女性高20%。这些数据强调了在区域组成研究中考虑性别和种族的重要性。本研究首次从美国国家健康与营养检查调查（NHANES）数据集中得出区域LMI和FMI参考表及曲线。这些参考曲线为涉及肌肉减少症、肥胖症、肌肉减少性肥胖症以及其他成分表型研究提供了一个有用的框架。此外，我们提供的用于可视化区域组成的软件工具，将有助于监测物理治疗、饮食或其他旨在实现更健康身体组成的尝试的进展情况。
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