Cheron Julian, Wyndham-Thomas Chloé, Sadeghi Niloufar, Naeije Gilles
Department of Neurology, Erasme University Hospital, Université Libre de Bruxelles , Brussels , Belgium.
Immunodeficiency Treatment Unit, Erasme University Hospital, Université Libre de Bruxelles , Brussels , Belgium.
Front Neurol. 2017 Mar 13;8:95. doi: 10.3389/fneur.2017.00095. eCollection 2017.
When secondary causes are excluded, mechanisms underlying central nervous system angiitis (ACNS) in human immunodeficiency virus (HIV)-infected patients are still not understood and optimal treatment remains undefined. We report here a patient with an untreated HIV infection who presented multiple ischemic strokes probably due to HIV-ACNS. ACNS signs on vessel-wall imaging magnetic resonance monitoring retracted with combined antiretroviral therapy without adjunct immunosuppressive drugs.
当排除继发原因后,人类免疫缺陷病毒(HIV)感染患者中枢神经系统血管炎(ACNS)的潜在机制仍不清楚,最佳治疗方法也尚未明确。我们在此报告一名未经治疗的HIV感染患者,其出现多次缺血性中风,可能是由于HIV-ACNS所致。在未使用辅助免疫抑制药物的情况下,联合抗逆转录病毒疗法使血管壁成像磁共振监测显示的ACNS体征消退。