Wagner R F, Cottel W I
Baylor University Medical Center, Dallas, Texas.
Urology. 1988 May;31(5):415-8. doi: 10.1016/0090-4295(88)90738-8.
It is often difficult to accurately judge the clinical tumor margins for extramammary Paget disease. Mohs micrographic surgery was used to extirpate a tumor which clinically measured 159.5 cm2. Following Mohs micrographic surgery, it was found that the actual dimensions of the tumor had been underestimated by 97 per cent. Since the Mohs micrographic surgeon microscopically examines the entire subcutaneous margin of the resected tumor, this technique provides an accurate method of determining the depth of tumor penetration. Mohs micrographic surgery allows for maximal conservation of normal tissue and yields higher cure rates than other conventional methods of treatment. When approaching tumors of the genitalia which may display poorly defined clinical margins, Mohs micrographic surgery should be considered the technique of choice.
对于乳腺外佩吉特病，准确判断临床肿瘤边界往往很困难。采用莫氏显微外科手术切除了一个临床测量面积为159.5平方厘米的肿瘤。在莫氏显微外科手术后发现，肿瘤的实际尺寸被低估了97%。由于莫氏显微外科医生会在显微镜下检查切除肿瘤的整个皮下边界，该技术提供了一种确定肿瘤浸润深度的准确方法。莫氏显微外科手术能够最大程度地保留正常组织，并比其他传统治疗方法产生更高的治愈率。当处理临床边界可能不清晰的生殖器肿瘤时，应考虑将莫氏显微外科手术作为首选技术。
