癌胚抗原快速染色有助于通过莫氏手术治疗的乳腺外佩吉特病的有限切除。

Rapid staining with carcinoembryonic antigen aids limited excision of extramammary Paget's disease treated by Mohs surgery.

作者信息

Harris D W, Kist D A, Bloom K, Zachary C B

机构信息

Department of Dermatology, University of Minnesota, Minneapolis 55455.

出版信息

J Dermatol Surg Oncol. 1994 Apr;20(4):260-4. doi: 10.1111/j.1524-4725.1994.tb01622.x.

DOI:10.1111/j.1524-4725.1994.tb01622.x

PMID:7513002

Abstract

Extensive extramammary Paget's (EMPD) disease of the perineum in a 68-year-old man was treated by Mohs surgery. To facilitate identification of involved tissue a rapid staining carcinoembryonic antigen was used. This technique proved a useful adjunct to conventional hemotoxylin-eosin (H&E) stains. It was especially useful in highlighting involvement in areas of marked dysplasia/artifact where discrimination is often difficult. It is recommended that such a technique offers considerable benefits over H&E staining when confronted by such tissue morphology.

摘要

一名68岁男性的会阴部广泛性乳腺外佩吉特病（EMPD）采用莫氏手术治疗。为便于识别受累组织，使用了快速染色癌胚抗原。该技术被证明是传统苏木精-伊红（H&E）染色的有用辅助手段。它在突出显示明显发育异常/人为假象区域的受累情况方面特别有用，而在这些区域进行鉴别往往很困难。建议在面对这种组织形态时，这种技术比H&E染色具有相当大的优势。