Nimri Laila, Sulaiman Mamuno, Hani Osama Bani
Department of Laboratory Medical Sciences, Jordan University of Science and Technology , Irbid , Jordan.
Department of General and Pediatric Surgery, Jordan University of Science and Technology , Irbid , Jordan.
JMM Case Rep. 2017 Jan 31;4(1):e005081. doi: 10.1099/jmmcr.0.005081. eCollection 2017 Jan.
Urinary tract infections (UTIs) remain common infections diagnosed in outpatients as well as hospitalized patients. Community-acquired UTIs are generally caused by and other members of the family is an opportunistic pathogen mainly affecting immunocompromised and hospitalized patients, particularly those who have received prior broad-spectrum antibacterial therapy. Urine samples were collected from 157 outpatients clinically diagnosed with UTI and from 100 healthy control subjects. Samples were cultured on differential media and non-motile lactose-non-fermentors were identified via the Remel RapID ONE system. The isolates were tested by the disc diffusion method against 17 antimicrobial agents. was isolated as a single organism from four patients having uncomplicated infections, and one from recurrent infection. None of these patients had an underlying risk factor for this pathogen. Identification of these isolates by the Remel-RapID ONE system was confirmed by gene amplification. The four isolates were resistant to lincomycin, nalidixic acid, oxacillin and penicillin G. These cases received monotherapy of oral co-trimoxazole. . Our findings alert urologists and diagnostic laboratories to the potential of complex infections in similar cases, and that this bacterium should not be ruled out.
尿路感染(UTIs)仍然是门诊患者和住院患者中常见的感染。社区获得性尿路感染通常由……以及……家族的其他成员引起,……是一种机会致病菌,主要影响免疫功能低下的患者和住院患者,特别是那些先前接受过广谱抗菌治疗的患者。从157例临床诊断为UTI的门诊患者和100例健康对照受试者中采集尿液样本。样本在鉴别培养基上培养,通过Remel RapID ONE系统鉴定非运动性乳糖不发酵菌。采用纸片扩散法对分离株进行17种抗菌药物的检测。在4例患有单纯性感染的患者中,……作为单一病原体被分离出来,1例来自复发性感染患者。这些患者均无该病原体的潜在危险因素。通过Remel-RapID ONE系统对这些分离株的鉴定通过……基因扩增得到证实。这4株分离株对林可霉素、萘啶酸、苯唑西林和青霉素G耐药。这些病例接受了口服复方新诺明的单一疗法。……我们的研究结果提醒泌尿科医生和诊断实验室,在类似病例中存在……复杂感染的可能性,不应排除这种细菌。