Riche D, Hantraye P, Guibert B, Naquet R, Loc'h C, Mazière B, Mazière M
Laboratoire de Physiologie Nerveuse, C.N.R.S., Gif-sur-Yvette, France.
Brain Res Bull. 1988 Mar;20(3):283-301. doi: 10.1016/0361-9230(88)90058-5.
An anatomical atlas has been constructed of the brain of the baboon (Papio papio) in the orbito-meatal plane (OM-plane) which is frequently used in experimental positron emission tomography (PET) investigations. The atlas comprises 12 photographic reproductions of histological brain sections separated by 2.5 mm intervals, and covers telencephalic to pontine brain stem levels. The anatomical atlas was used in analysis of some PET scan images obtained after administration of either a benzodiazepine (BZ) antagonist, (11C)-Ro 15-1788, or a dopamine D2 receptor antagonist, (76Br)-bromospiperone. Since PET camera detects radiation emitted from a slice of tissue of 15 mm thickness, each PET image corresponds to the tissue represented on six levels of the anatomical atlas. In optimal conditions, the PET image shows a pattern of receptor labelling reminiscent of anatomical structures in the atlas. Sometimes, however, the superimposition of different labelled structures yields a PET image which lacks any apparent resemblance with individual anatomical structures. In these cases, the analysis of the PET scan must rely on the anatomical atlas, as well as available data on the distribution of specific binding sites.
已构建狒狒（巴氏狒狒）大脑在眶耳平面（OM平面）的解剖图谱，该平面常用于实验性正电子发射断层扫描（PET）研究。该图谱包含12张组织学脑切片的照片复制品，切片间隔为2.5毫米，涵盖端脑至脑桥脑干水平。该解剖图谱用于分析在给予苯二氮䓬（BZ）拮抗剂（11C）-Ro 15-1788或多巴胺D2受体拮抗剂（76Br）-溴螺哌隆后获得的一些PET扫描图像。由于PET相机检测的是15毫米厚的组织切片发出的辐射，每张PET图像对应于解剖图谱六个层面上所代表的组织。在最佳条件下，PET图像显示出一种受体标记模式，让人联想到图谱中的解剖结构。然而，有时不同标记结构的叠加会产生一张与单个解剖结构没有明显相似之处的PET图像。在这些情况下，PET扫描的分析必须依靠解剖图谱以及特定结合位点分布的现有数据。
