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韦尼克-科尔萨科夫综合征:识别与治疗

Wernicke-Korsakoff syndrome: recognition and treatment.

作者信息

Donnelly Alexander

机构信息

Colman Centre for Specialist Rehabilitation Services, Norwich, England.

出版信息

Nurs Stand. 2017 Mar 29;31(31):46-53. doi: 10.7748/ns.2017.e10440.

Abstract

Wernicke-Korsakoff syndrome is a potentially debilitating and fatal condition that is caused by thiamine (vitamin B1) deficiency in the brain. It can be treated effectively or prevented completely; however, the condition is often undiagnosed and inadequately managed. Wernicke-Korsakoff syndrome is commonly considered to be specific to individuals who misuse alcohol; however, there are many other predisposing factors and causes associated with the condition. This article aims to raise awareness of Wernicke-Korsakoff syndrome, to enable nurses in all practice settings to recognise the signs, symptoms and risk factors associated with the condition and be informed about available treatments. Increased awareness aims to improve early diagnosis of the condition, enabling effective treatment and improving patients' symptoms, such as cognitive impairment.

摘要

韦尼克-科尔萨科夫综合征是一种可能使人衰弱甚至致命的疾病,由大脑中硫胺素(维生素B1)缺乏引起。它可以得到有效治疗或完全预防;然而,这种疾病常常未被诊断出来,且治疗不当。韦尼克-科尔萨科夫综合征通常被认为是酗酒者特有的疾病;然而,还有许多其他诱发因素和病因与该疾病相关。本文旨在提高对韦尼克-科尔萨科夫综合征的认识,使所有执业环境中的护士能够识别与该疾病相关的体征、症状和风险因素,并了解可用的治疗方法。提高认识旨在改善该疾病的早期诊断,实现有效治疗并改善患者的症状,如认知障碍。

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