Serim Demirgoren Burcu, Ozbek Aylin, Ormen Murat, Kavurma Canem, Ozer Esra, Aydın Adem
1 MD, Department of Child and Adolescent Psychiatry, Faculty of Medicine, Dokuz Eylul University, Izmir, Turkey.
2 MD, Department of Biochemistry, Faculty of Medicine, Dokuz Eylul University, Izmir, Turkey.
J Int Med Res. 2017 Apr;45(2):843-848. doi: 10.1177/0300060517700013. Epub 2017 Mar 29.
Objective This study aimed to assess the possible association of high breast milk sodium levels with postpartum depression and anxiety. Methods A total of 150 mothers and their healthy, exclusively breastfed newborns aged 8 to 15 days were recruited. Mothers were asked to complete scales for evaluation of postnatal depression and anxiety following an interview for consent and sociodemographic data collection. Breast milk samples were obtained to measure sodium and potassium (K) levels. Results Forty-nine mothers had higher than expected breast milk Na concentrations and a high Na/K ratio. These mothers scored significantly higher on the scales of postnatal depression and state anxiety ( P = 0.018 and P = 0.048, respectively). Conclusions This study shows that compared to normal breast milk Na levels and Na/K ratio, high breast milk Na and high Na/K ratio, with possible serious consequences in infants, are associated with maternal depressive and anxious symptoms in the postpartum period.
目的 本研究旨在评估母乳钠水平升高与产后抑郁和焦虑之间可能存在的关联。方法 共招募了150名母亲及其8至15日龄健康、纯母乳喂养的新生儿。在进行同意访谈和社会人口学数据收集后，要求母亲们完成产后抑郁和焦虑评估量表。采集母乳样本以测量钠和钾（K）水平。结果 49名母亲的母乳钠浓度高于预期且钠/钾比值较高。这些母亲在产后抑郁和状态焦虑量表上的得分显著更高（分别为P = 0.018和P = 0.048）。结论 本研究表明，与正常母乳钠水平和钠/钾比值相比，母乳钠升高和钠/钾比值升高可能对婴儿造成严重后果，且与产后母亲的抑郁和焦虑症状相关。
