真菌中细胞器的空间组织：来自数学建模的见解
Spatial organization of organelles in fungi: Insights from mathematical modelling.
作者信息
Lin Congping, Steinberg Gero
机构信息
Mathematics, University of Exeter, North Park Road, Exeter EX4 4QF, UK.
School of Biosciences, University of Exeter, Stocker Road, Exeter EX4 4QD, UK; Donders Chair, University of Utrecht, Department of Biology, Padualaan 8, 3584 CH Utrecht, The Netherlands.
出版信息
Fungal Genet Biol. 2017 Jun;103:55-59. doi: 10.1016/j.fgb.2017.03.006. Epub 2017 Mar 25.
Mathematical modelling in cellular systems aims to describe biological processes in a quantitative manner. Most accurate modelling is based on robust experimental data. Here we review recent progress in the theoretical description of motor behaviour, early endosome motility, ribosome distribution and peroxisome transport in the fungal model system Ustilago maydis and illustrate the power of modelling in our quest to understand molecular details and cellular roles of membrane trafficking in filamentous fungi.
细胞系统中的数学建模旨在以定量方式描述生物过程。最精确的建模基于可靠的实验数据。在此，我们回顾了真菌模型系统玉米黑粉菌中运动行为、早期内体运动、核糖体分布和过氧化物酶体运输的理论描述方面的最新进展，并阐述了建模在我们理解丝状真菌中膜运输的分子细节和细胞作用的探索中的作用。
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