Kim Seon-Ha, Jo Min-Woo, Ock Minsu, Lee Hyeon-Jeong, Lee Jong-Won
Department of Nursing, College of Nursing, Dankook University, Cheonan.
Department of Preventive Medicine, University of Ulsan College of Medicine, Seoul.
Patient Prefer Adherence. 2017 Mar 14;11:531-536. doi: 10.2147/PPA.S129856. eCollection 2017.
The aim of this study is to determine the utility of breast cancer health states using the standard gamble (SG) and visual analog scale (VAS) methods in the Korean general population.
Eight hypothetical breast cancer health states were developed based on patient education material and previous publications. Data from 509 individuals from the Korean general population were used to evaluate breast cancer health states using the VAS and the SG methods, which were obtained via computer-assisted personal interviews. Mean utility values were calculated for each human papillomavirus (HPV)-related health state.
The rank of health states was identical between two valuation methods. SG values were higher than VAS values in all health states. The utility values derived from SG were 0.801 (noninvasive breast cancer with mastectomy and followed by reconstruction), 0.790 (noninvasive breast cancer with mastectomy only), 0.779 (noninvasive breast cancer with breast-conserving surgery and radiation therapy), 0.731 (invasive breast cancer with surgery, radiation therapy, and/or chemotherapy), 0.610 (locally advanced breast cancer with radical mastectomy with radiation therapy), 0.587 (inoperable locally advanced breast cancer), 0.496 (loco-regional recurrent breast cancer), and 0.352 (metastatic breast cancer).
Our findings might be useful for economic evaluation of breast cancer screening and interventions in general populations.
本研究旨在通过标准博弈法（SG）和视觉模拟评分法（VAS）来确定韩国普通人群中乳腺癌健康状态的效用。
基于患者教育材料和以往出版物开发了8种假设的乳腺癌健康状态。来自韩国普通人群的509名个体的数据用于通过计算机辅助个人访谈获得的VAS和SG方法评估乳腺癌健康状态。计算了每个人乳头瘤病毒（HPV）相关健康状态的平均效用值。
两种评估方法对健康状态的排序相同。在所有健康状态下，SG值均高于VAS值。SG得出的效用值分别为0.801（乳房切除术后重建的非浸润性乳腺癌）、0.790（仅行乳房切除术的非浸润性乳腺癌）、0.779（保乳手术加放射治疗的非浸润性乳腺癌）、0.731（手术、放射治疗和/或化疗的浸润性乳腺癌）、0.610（根治性乳房切除术加放射治疗的局部晚期乳腺癌）、0.587（不可手术的局部晚期乳腺癌）、0.496（局部区域复发性乳腺癌）和0.352（转移性乳腺癌）。
我们的研究结果可能有助于对普通人群中的乳腺癌筛查和干预措施进行经济评估。
